He, Baoshan Wang, Kai
Published in
Microchimica Acta
A “signal off” aptasensor has been developed to detect deoxynivalenol (DON). DON aptamers (Apt) were used as biological recognition elements, nickel ferrite nanotubes (NiFe2O4 NTs) are used as the base material to increase the surface area of the electrode, and the [email protected] NRs were used as carriers for loading signal labels thionine (Thi) and complem...
DEGRASSI, G. CARPENTIERI-PIPOLO, V.
Fusarium Head Blight (FHB) is predominately caused by F. graminearum whose infection not only results in yield loss, but also contaminates grains with mycotoxins, such as deoxynivalenol (DON), which pose a great threat to human and animal health. Application of chemical fungicides remains the main approach to control FHB due to the lack of effectiv...
Ookawara, Toa Aihara, Ryota Morimoto, Ai Iwashita, Naoki Kurata, Keigo Takagi, Yoshiichi Miyasaka, Atsushi Kushiro, Masayo Miyake, Shiro Fukuyama, Tomoki
...
Published in
Toxicological sciences : an official journal of the Society of Toxicology
Previously, researchers have demonstrated that mycotoxin deoxynivalenol significantly enhances immunocyte activation. However, the interaction between deoxynivalenol exposure and immune disorders remains unclear. In this study, we aimed to investigate whether acute and subacute oral exposure to deoxynivalenol exacerbates the development of respirat...
Wang, Xiaodan Yang, Dajin Qin, Mei Xu, Haibin Zhang, Lishi Zhang, Lei
Published in
Mycotoxin research
Deoxynivalenol (DON) is one of the most commonly found mycotoxins across the world, and it mainly contaminates staple food crops. This study aims to evaluate the dietary exposure of DON and to provide a geographical profile of DON exposure in China. The concentrations of DON and its acetylated derivatives in 15,004 cereal samples (10,192 wheat flou...
Zhang, Jiajia You, Li Wu, Wenda Wang, Xu Chrienova, Zofia Nepovimova, Eugenie Wu, Qinghua Kuca, Kamil
Published in
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
During the last decade, the neurotoxicity of the trichothecenes T-2 toxin and deoxynivalenol (DON) has been a major concern, and many important findings have been reported on this topic. Through a summary of relevant research reports in recent years, we discuss the potential neurotoxic mechanisms of T-2 toxin and DON. In neuronal cells, T-2 toxin i...
Kalagatur, Naveen Kumar Abd_Allah, Elsayed Fathi Poda, Sudhakar Kadirvelu, Krishna Hashem, Abeer Mudili, Venkataramana Siddaiah, Chandranayaka
Published in
Saudi Journal of Biological Sciences
Deoxynivalenol (DON) is Fusarium mycotoxin that is frequently found in many cereal-based foods, and its ingestion has a deleterious impact on human health. In this investigation, we studied the mechanism of DON-induced neurotoxicity and followed by cytoprotective efficacy of quercetin (QUE) in contradiction of DON-induced neurotoxicity through asse...
Ledur, Pauline Christ Santurio, Janio M
Published in
Toxicon : official journal of the International Society on Toxinology
Mycotoxins are toxic secondary metabolites produced by fungus which cause worldwide concern regarding food and feed safety. Ochratoxin A (OTA), fumonisin B1 (FB1) and deoxynivalenol (DON) are some of the main mycotoxins and oxidative stress is the main mechanism of toxicity. Thereby, this study investigates the in vitro cytoprotective effects of cu...
Tran, Anh-Tuan Kluess, Jeannette Kersten, Susanne Berk, Andreas Paulick, Marleen Schatzmayr, Dian Dänicke, Sven Frahm, Jana
Published in
Mycotoxin Research
The main objective of this study was to evaluate the effects of sodium sulfite (SoS) treatment of maize and its impact on the porcine immune system in the presence of an LPS-induced systemic inflammation. Control maize (CON) and Fusarium -toxin contaminated maize (FUS) were wet-preserved (20% moisture) for 79 days with (+) or without (−) SoS and th...
Guo, Yongpeng Huo, Xueting Zhao, Lihua Ma, Qiugang Zhang, Jianyun Ji, Cheng Zhao, Lihong
Published in
Probiotics and antimicrobial proteins
Mycotoxins are toxic secondary metabolites produced by toxigenic fungi that commonly contaminate agricultural crops. The purpose of the current study was to evaluate whether Bacillus subtilis ANSB060, Bacillus subtilis ANSB01G, and Devosia sp. ANSB714-based mycotoxin biodegradation agent (MBA) could alleviate the negative effects of naturally moldy...
Ge, Lei Lin, Ziman Le, Guannan Hou, Lili Mao, Xinru Liu, Shuiping Liu, Dandan Gan, Fang Huang, Kehe
Published in
Food and Chemical Toxicology
• Nontoxic-dose DON aggravates LPS-induced cellular inflammatory response in IPEC-J2 cell monolayers. • Nontoxic-dose DON aggravates LPS-induced decrease and distribution disorder of tight junction in IPEC-J2 cell monolayers. • Nontoxic-dose DON aggravates LPS-induced inflammatory response and tight junction disorder by activating NF-κB and LC3B.
