Absence of Dipeptidyl Peptidase 3 Increases Oxidative Stress and Causes Bone Loss.
...Published in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Controlling oxidative stress through the activation of antioxidant pathways is crucial in bone homeostasis, and impairments of the cellular defense systems involved contribute to the pathogenesis of common skeletal diseases. In this work we focused on the dipeptidyl peptidase 3 (DPP3), a poorly investigated ubiquitous zinc-dependent exopeptidase ac...
