Bonnet, Diane Marie Valerie Tirot, Louis Grob, Stefan Jullien, Pauline Emilie
Published in
Molecular plant-microbe interactions : MPMI
DNA methylation is an important epigenetic mark required for proper gene expression and silencing of transposable elements. DNA methylation patterns can be modified by environmental factors such as pathogen infection, in which modification of DNA methylation can be associated with plant resistance. To counter the plant defense pathways, pathogens p...
Sun, Zhifu Braga-Neto, Manuel B Xiong, Yuning Bhagwate, Adytia V Gibbons, Hunter R Sagstetter, Mary R Hamdan, Feda H Baheti, Saurabh Friton, Jessica Nair, Asha
...
Published in
Journal of Crohn's & colitis
The development of Crohn's disease [CD] involves immune cell signalling pathways regulated by epigenetic modifications. Aberrant DNA methylation has been identified in peripheral blood and bulk intestinal tissue from CD patients. However, the DNA methylome of disease-associated intestinal CD4+ lymphocytes has not been evaluated. Genome-wide DNA met...
Leduque, Basile Edera, Alejandro Vitte, Clementine Quadrana, Leandro
ABSTRACT Epigenetic regulations, including chromatin accessibility, nucleosome positioning, and DNA methylation intricately shape genome function. However, current chromatin profiling techniques relying on short-read sequencing technologies face limitations in adequately characterising repetitive genomic regions and detecting multiple chromatin fea...
Ho, PJ Khng, AJ Tan, BKT Lim, GH Tan, SM Tan, VKM Tan, RSYC Lim, EH Iau, PTC Chew, YJ
...
10.1186/s13058-023-01730-4 / Breast Cancer Research / 25 / 1 / 136- / completed
Bruce, Kimberley D Eckel, Robert H
Published in
The Journal of clinical endocrinology and metabolism
Gade, Madhuri Gardner, Jasmine M Jain, Prashant Laurino, Paola
Published in
Chembiochem : a European journal of chemical biology
We have studied the adenosine binding specificities of two bacterial DNA methyltransferases, Taq methyltransferase (M.TaqI), and HhaI methyltransferase (M.HhaI). While they have similar cofactor binding pocket interactions, experimental data showed different specificity for novel S-nucleobase-l-methionine cofactors (SNMs; N=guanosyl, cytidyl, uridy...
Moissiard, Guillaume Mirouze, Marie Carles, Cristel C. Vitte, Clémentine
Published in
Frontiers in Plant Science
Wang, YaXuan Wang, Jinfeng He, JiaXing Ji, Bo Pang, ZhongQi Wang, JianShe Liu, Yang Ren, MingHua
Published in
Frontiers in Immunology
Background Pre-mRNA processing factor 19 (PRPF19) is an E3 ligase that plays a crucial role in repairing tumor-damaged cells and promoting cell survival. However, the predictive value and biological function of PRPF19 in bladder urothelial carcinoma (BLCA) require further investigation. Methods In this study, we utilized transcriptomic data and bla...
Yang, Hui Wang, Yiman Zhang, Yong
Published in
BMC genomics
H3K9me3 and DNA methylation co-marked CpG-rich regions (CHMs) are functionally important in mouse pre-implantation embryos, but their characteristics in other biological processes are still largely unknown. In this study, we performed a comprehensive analysis to characterize CHMs during 6 mouse developmental processes, identifying over 2,600 CHMs e...
Tan, Sheng Zhang, Jie Peng, Yonglin Du, Wenfei Yan, Jingxuan Fang, Qin
Published in
Frontiers in Microbiology
Introduction Grass carp reovirus (GCRV), a member of the Aquareovirus genus in the Reoviridae family, is considered to be the most pathogenic aquareovirus. Productive viral infection requires extensive interactions between viruses and host cells. However, the molecular mechanisms underlying GCRV early infection remains elusive. Methods In this stud...
