El Zowalaty, Mohamed E Falgenhauer, Linda Forsythe, Stephen Helmy, Yosra A
Published in
Journal of global antimicrobial resistance
Antimicrobial-resistant bacteria of the order Enterobacterales are emerging threats to global public and animal health, leading to morbidity and mortality. The emergence of antimicrobial-resistant, livestock-associated pathogens is a great public health concern. The genera Enterobacter and Lelliottia are ubiquitous, facultatively anaerobic, motile,...
Nakayama, Hirokazu Kamoda, Yoshimasa Tanuma, Michiya Kato, Toshiaki Usuki, Kensuke
Published in
Journal of Pharmaceutical Health Care and Sciences
Background Erythrocyte transfusion is an indispensable component of supportive care after hematopoietic stem cell transplantation (HSCT). However, HSCT recipients are susceptible to the development of acute kidney injury (AKI) with multifactorial causes. We report a case of a rapid elevation in serum creatinine associated with deferoxamine after co...
Zeng, Haiyan Tan, Yujing Su, Jianhui Gao, Fei Lei, Tao Liang, Bingshao
Published in
Journal of global antimicrobial resistance
The co-emergence of mcr and carbapenem resistance genes in Gram-negative bacteria is a serious problem. This study aims to clarify the genetic characteristic of one novel multidrug-resistant Enterobacter kobei EC1382 with mcr-9 causing urinary tract inflammation in an infant. Antimicrobial drug susceptibility testing was performed for this isolate ...
Baliga, Pallavi Goolappa, Puneeth Thadooru Shekar, Malathi Kallappa, Girisha Shivani
Published in
Probiotics and antimicrobial proteins
Multidrug-resistant bacteria are emerging as a major global threat to public health. Bacteriophages are an important source of antimicrobial enzymes and could be developed as an alternative antibiotic candidate. This study investigates the antibacterial capacity of the endolysin LysE against Aeromonas hydrophila. The endolysin LysE gene was cloned ...
Werner, Guido Abu Sin, Muna Bahrs, Christina Brogden, Sandra Feßler, Andrea T. Hagel, Stefan Kaspar, Heike Köck, Robin Kreienbrock, Lothar Krüger-Haker, Henrike
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Published in
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
„One Health“ bezeichnet ein Konzept, das die Gesundheit von Menschen, Tieren und der Umwelt miteinander verbindet. In Deutschland gibt es umfangreiche Daten zur Antibiotikaresistenz (AMR) und multiresistenten Erregern (MRE) in der Human- und Veterinärmedizin sowie aus Untersuchungen in verschiedenen Umweltkompartimenten (Boden, Wasser, Abwasser). D...
René, Renzhammer Sebastian, Vetter Marlies, Dolezal Lukas, Schwarz Annemarie, Käsbohrer Andrea, Ladinig
Published in
Porcine health management
Post-weaning diarrhoea (PWD) is a frequent, multifactorial disease of piglets leading to increased mortality rates and high economic losses. Due to the emergence of multi-resistant Escherichia coli isolates and the ban of zinc oxide (ZnO) in the EU since June 2022, alternative measures to prevent PWD are urgently needed. While an abundance of feed ...
Ragupathi, Naveen Kumar Devanga Muthuirulandi Sethuvel, Dhiviya Prabaa Gopikrishnan, Mohanraj Dwarakanathan, Hariharan Triplicane Murugan, Dhivya Biswas, Indranil Bakthavachalam, Yamuna Devi Murugesan, Malathi George Priya Doss, C Monk, Peter N
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Published in
Microbial pathogenesis
Persistent antibiotic use results in the rise of antimicrobial resistance with limited or no choice for multidrug-resistant (MDR) and extensively drug resistant (XDR) bacteria. This necessitates a need for alternative therapy to effectively combat clinical pathogens that are resistant to last resort antibiotics. The study investigates hospital sewa...
Rose, T. F. Amal Kannan, Porteen Ruban, S. Wilfred Srinivas, Kandhan Milton, Arockiasamy Arun Prince Ghatak, Sandeep Elango, A. Rajalakshmi, S. Sundaram, Sureshkannan
Published in
3 Biotech
Salmonella enterica serovar Kentucky is a frequent cause for clinical infections in human patients. They are isolated and reported with multidrug resistance from the foods of animal origin from various countries. However, studies inferring the colistin resistance are limited. Hence, the current study reports the genetic factors and genomic analysis...
Coz, Elsa Jouy, Eric Cazeau, Géraldine Jarrige, Nathalie Chauvin, Claire Delignette-Muller, Marie Laure
Colistin resistance has been the subject of much attention since mcr genes encoding plasmid-mediated colistin resistance description in 2015. To date, surveillance data about resistance levels encountered in food-producing animals are scarce. In France, the Resapath dataset, consisting in a large collection of disk diffusion antibiogram results tra...
Landa, Guillermo Alejo, Teresa Sauzet, Theo Laroche, Julian Sebastian, Victor Tewes, Frederic Arruebo, Manuel
Compared to parenteral administration of colistin, its direct pulmonary administration can maximize lung drug deposition while reducing systemic adverse side effects and derived nephrotoxicity. Current pulmonary administration of colistin is carried out by the aerosolization of a prodrug, colistin methanesulfonate (CMS), which must be hydrolized to...