Stohs, Sidney J
Published in
Phytotherapy research : PTR
Citrus aurantium L. (bitter orange) extracts that contain p-synephrine as the primary protoalkaloid are widely used for weight loss/weight management, sports performance, appetite control, energy, and mental focus and cognition. Questions have been raised about the safety of p-synephrine because it has some structural similarity to ephedrine. This ...
Bakhyia, Nadiya Dusemund, Birgit Richter, Klaus Lindtner, Oliver Hirsch-Ernst, Karen Ildico Schäfer, Bernd Lampen, Alfonso
Published in
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz
Synephrin ist ein sympathomimetisches Phenylethylaminderivat aus Zitrusfrüchten. Der Pflanzeninhaltsstoff wird in Form von Extrakten aus Bitterorangen (Citrus aurantium) und oft in Kombination mit Koffein Nahrungsergänzungsmitteln zugesetzt, die zur Gewichtsabnahme bzw. Steigerung der körperlichen Leistungsfähigkeit angeboten werden. Im vorliegende...
Oueslati, Amel Salhi-Hannachi, Amel Luro, François Vignes, Hélène MOURNET, Pierre Ollitrault, Patrick
The mandarin horticultural group is an important component of world citrus production for the fresh fruit market. This group formerly classified as C. reticulata is highly polymorphic and recent molecular studies have suggested that numerous cultivated mandarins were introgressed by C. maxima (the pummelos). C. maxima and C. reticulata are also the...
Sanei-Dehkordi, Alireza Sedaghat, Mohammad Mehdi Vatandoost, Hassan Abai, Mohammad Reza
Published in
Journal of arthropod-borne diseases
Recently, essential oils and extracts derived from plants have received much interest as potential bio-active agents against mosquito vectors. The essential oils extract from fresh peel of ripe fruit of Citrus aurantium and Citrus paradisi were tested against mosquito vector Anopheles stephensi (Diptera: Culicidae) under laboratory condition. Then ...
Yu, Guo-Hua Yang, Hong-Jun Li, Jun-Fang Geng, Ya Dong, Ling Xu, Hai-Yu
Published in
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
In this study, a ultra-high-pressure liquid chromatography coupled with linear ion trap-Orbitrap tandem mass spectrometry (UHPLC-LTQ-Orbitrap-MS/MS) method was developed to analyze the chemical components in Citrus aurantium. C. aurantium were extracted with 75% methanol, and we applied a Thermo Scientific BDS Hypersil C₁₈ column (2.1 mm×150 mm, 2....
Gutiérrez-Hellín, Jorge Del Coso, Juan
Published in
British journal of clinical pharmacology
p-Synephrine is a protoalkaloid widely used in dietary supplements for weight management because of its purported thermogenic effects. However, there is a lack of scientific information about its effectiveness to increase fat metabolism during exercise. The purpose of this investigation was to determine the effects of an acute ingestion of p-syneph...
Shara, Mohd Stohs, Sidney J Mukattash, Tareq L
Published in
Phytotherapy research : PTR
Bitter orange (Citrus aurantium) extract and its primary protoalkaloid p-synephrine are widely consumed in combination with multiple herbal ingredients for weight management and sports performance. p-Synephrine is also present in juices and foods derived from a variety of Citrus species. Questions exist regarding the safety of p-synephrine because ...
Motaghi, Sahel Jonaidi, Hossein Abbasnejad, Mehdi Usofi, Manouchehr Khaki, Mohammadreza Afarinesh Sheibani, Vahid
Published in
Comparative Clinical Pathology
Anxiety disorders have a relatively high prevalence in most countries. Chemical drugs used to treat anxiety have some unwanted side effects. Therefore, using medicinal plants is useful. Citrus aurantium L. (CaL) flowers are used in Iran to treat anxiety as a folk medicine. We investigated its anxiolytic and sedative effects. We used elevated plus m...
Curk, Franck Ollitrault, Frédérique Garcia-Lor, Andres Luro, François Navarro, Luis Ollitrault, Patrick
Ratamess, Nicholas A Bush, Jill A Kang, Jie Kraemer, William J Stohs, Sidney J Nocera, Vincenzo G Leise, Megan D Diamond, Keith B Campbell, Sara C Miller, Howard B
...
Published in
Journal of the American College of Nutrition
The purpose of this study was to examine the metabolic, lipolytic, and cardiovascular responses to supplementation with p-synephrine alone and in combination with caffeine during resistance exercise (RE). Twelve healthy men performed a control RE protocol (6 × 10 repetitions of squats) and were randomly assigned (using a double-blind crossover desi...
