Adam, R. Avisar, E. Ariche, A. Giachetti, S. Azoulay, D. Castaing, D. Kunstlinger, F. Levi, F. Bismuth, F.
Published in
Annals of Surgical Oncology
Background: Surgical resection is the most effective treatment for colorectal liver metastases but only a minority of patients are candidates for a potentially curative resection. Our experience with neoadjuvant chemotherapy followed by resection and five years survival analysis of the patients treated is presented. Methods: Between February of 198...
Park, Ji Young Kim, Si-Young Lee, Jae Jin Yoon, Hwi Joong Cho, Kyung Sam
Published in
Cancer research and treatment : official journal of Korean Cancer Association
The modified chronomodulated infusion of oxaliplatin, 5-FU and leucovorin is effective and tolerable, but the number of patients was too small. Further study will be needed to confirm the efficacy of this regimen with a larger population of patients.
Terzoli, Edmondo Garufi, Carlo Zappalà, Albina Rita Vanni, Barbara Pugliese, Patrizia Cappellini, Giancarlo Antonini Aschelter, Anna Maria Perrone, Maria Giannarelli, Diana
Published in
Journal of Cancer Research and Clinical Oncology
Purpose. The best way to deliver infusional 5-fluorouracil (5-FU) and folinic acid (FA) has yet to be determined. The aim of this prospective phase II trial was to verify the tolerability, activity and efficacy of chronomodulated 5-FU-FA (FF5–16) every 3 weeks in 48 untreated patients (group A), and 28 pretreated and four non-measurable, advanced c...
Seki, K Chisaka, M Eriguchi, M Yanagie, H Hisa, T Osada, I Sairenji, T Otsuka, K Halberg, F
Published in
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Current Western medical treatment lays its main emphasis on evidence-based medicine (EBM) and cure is assessed by quantifying the effects of treatment statistically. In contrast, in Chinese medicine, cure is generally assessed by evaluating the patient's "pattern" (Zheng) [cf. Glossary] and medicines are prescribed according to this. We believe tha...
Silva, C.S. Torres, L.A.G.M.M. Rahal, A. Terra Filho, J. Vianna, E.O.
Fitness improvement was used to compare morning with afternoon exercise periods for asthmatic children. Children with persistent moderate asthma (according to GINA criteria), 8 to 11 years old, were divided into 3 groups: morning training group (N = 23), afternoon training group (N = 23), and non-training group (N = 23). The program was based on tw...
Lévi, Francis
Published in
Cancer Causes & Control
BackgroundCell physiology is regulated along the 24-h time scale by a circadian timing system composed of molecular clocks within each cell and a central coordination system in the brain. The mammalian molecular clock is made of interconnected molecular loops involving at least 12 circadian genes. The cellular clocks are coordinated by the suprachi...
Moser, Maximilian Frühwirth, Matthias Penter, Reiner Winker, Robert
Published in
Cancer Causes & Control
Chronobiology has identified a multitude of rhythms within our body as well as within each living cell. Some of these rhythms, such as the circadian and circannual, interact with our environment, while others run on their own, but are often coupled to the circadian or to other body rhythms. Recent evidence shows that these rhythms might be more imp...
ROSAS, Ralph F MORENO, Claudia Roberta de Castro
In several treatment regimens, the recognition of chronobiology contributes to the therapeutic process through the effective use of temporization protocols. The purpose of the present study was to evaluate the relationship between the tic treatment and the time of day when such treatment was performed, as well as the chronotype of orthopedic and rh...
ROSAS, Ralph F MORENO, Claudia Roberta de Castro
In several treatment regimens, the recognition of chronobiology contributes to the therapeutic process through the effective use of temporization protocols. The purpose of the present study was to evaluate the relationship between the tic treatment and the time of day when such treatment was performed, as well as the chronotype of orthopedic and rh...
ROSAS, Ralph F MORENO, Claudia Roberta de Castro
In several treatment regimens, the recognition of chronobiology contributes to the therapeutic process through the effective use of temporization protocols. The purpose of the present study was to evaluate the relationship between the tic treatment and the time of day when such treatment was performed, as well as the chronotype of orthopedic and rh...
