Sato, Yasushi Takayama, Tetsuji Sagawa, Tamotsu Okamoto, Tetsuro Miyanishi, Koji Sato, Tsutomu Araki, Hironobu Iyama, Satoshi Abe, Seiichiro Murase, Kazuyuki
...
Published in
Cancer Chemotherapy and Pharmacology
Purpose: To determine the recommended dose (RD) of cis-diammine-glycolatoplatinum (nedaplatin) when given concurrently with 5-FU and high dose radiation therapy in the treatment of esophageal cancer. The purpose of the phase II trial is to determine efficacy and further define the side effect profile. Methods: Twenty-six patients with clinical stag...
Duong, Cuong P. Hicks, Rodney J. Weih, LeAnn Drummond, Elizabeth Leong, Trevor Michael, Michael Thomas, Robert J. S.
Published in
European Journal of Nuclear Medicine and Molecular Imaging
PurposeThe purpose of this study was to evaluate the impact of FDG-PET following chemoradiotherapy (CRT) on treatment planning and survival in patients with oesophageal cancer (OC).MethodsFifty-three consecutive OC patients had a post-treatment PET scan to evaluate tumour response to CRT prior to possible surgery. Baseline pre-CRT PET was performed...
Yorozu, Atsunori Toya, Kazuhito Dokiya, Takushi
Published in
Esophagus
BackgroundTo assess the long-term efficacy and the pattern of failure of concurrent chemoradiotherapy followed by high dose rate (HDR) brachytherapy for stage T2-3 N0-1 M0 esophageal carcinoma.MethodsForty-six patients with clinical stage T2-3 N0-1 M0 esophageal cancer received concurrent chemoradiotherapy followed by HDR brachytherapy. The chemoth...
Ichimura, Hideo Usui, Shingo Okazaki, Hiroo Konishi, Taisuke Osaka, Motoo Jikuya, Tomoaki Nakayama, Hidetsugu Kikuchi, Kazunori Inadome, Yukinori Onizuka, Masataka
...
Published in
Surgery Today
We report a case of invasive thymoma with intracardiac extension, resulting from the progression of intracaval growth, in a 56-year-old woman. Initially, the patient received two courses of chemotherapy, but the tumor showed only a modest response; however, subsequent radiotherapy reduced the tumor size further and the intracardiac lesion disappear...
Kobayashi, Masashi Matsui, Kaoru Hirashima, Tomonori Nitta, Takashi Sasada, Shinji Tada, Takuhito Minakuchi, Kazuo Furukawa, Mitsugi Ogata, Yoshitaka Kawase, Ichiro
...
Published in
International Journal of Clinical Oncology
BackgroundThe combination of chemotherapy and thoracic radiation therapy (TRT) is considered as a standard treatment for locally advanced non-small-cell lung cancer (NSCLC). Although the frequent interaction of anticancer agents and irradiation may produce stronger radio-sensitizing effects, the daily administration of these agents is complicated. ...
Maemura, Kosei Takao, Sonshin Shinchi, Hiroyuki Noma, Hidetoshi Mataki, Yukou Kurahara, Hiroshi Jinnouchi, Seishi Aikou, Takashi
Published in
Journal of Hepato-Biliary-Pancreatic Surgery
Background/PurposeThe purpose of this study was to estimate the usefulness of positron emission tomography (PET) in deciding on strategies for the treatment of pancreatic cancer. The following two parameters were evaluated: the ability of PET to provide an estimation of the progression of pancreatic cancer, and the ability of PET to predict surviva...
Motoyama, Satoru Sugiyama, Toshihiro Ueno, Yasuharu Okamoto, Hiroshi Takasawa, Shin Nanjo, Hiroshi Watanabe, Hitoshi Maruyama, Kiyotomi Okuyama, Manabu Ogawa, Jun-ichi
...
Published in
Annals of Surgical Oncology
BackgroundThe prognosis for patients with locally advanced thoracic esophageal cancer is extremely unfavorable. We have been administering neoadjuvant chemoradiotherapy (CRT) followed by esophagectomy to these patients and studying whether REG I expression in untreated endoscopic biopsy specimens is predictive of patient responsiveness to CRT and/o...
Katori, Hideaki Tsukuda, Mamoru Taguchi, Takahide
Published in
Cancer Chemotherapy and Pharmacology
PurposeThe aim of this study was to evaluate the efficacy and toxicity of concurrent chemoradiotherapy using cisplatin (CDDP), 5-fluorouracil (5-FU), methotrexate (MTX) and leucovorin (LV) (PFML) in patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN).MethodsSeventy-seven patients with previously untreated stages III–...
Homma, Akihiro Furuta, Yasushi Oridate, Nobuhiko Suzuki, Fumiyuki Higuchi, Eisaku Nishioka, Takeshi Shirato, Hiroki Nagahashi, Tatsumi Yagi, Katsunori Fukuda, Satoshi
...
Published in
International Journal of Clinical Oncology
BackgroundChemoradiotherapy (CRT) is becoming more widely used for head and neck cancer. However, there are conflicting theories regarding the best management options for patients with advanced nodal disease.MethodsFrom 1990 to 1999, we treated 96 patients with N1-N2 neck disease by concomitant CRT for organ preservation, using weekly carboplatin o...
Strosberg, Jonathan Hoffe, Sarah Gardner, Nancy Choi, Junsung Kvols, Larry
Published in
Neuroendocrinology
Background/Aims: The use of chemoradiation in the management of locally advanced pancreatic endocrine tumors has not been reported in the medical literature. Patients with unresectable tumors are often included in trials of systemic chemotherapy, and use of external beam radiation has been only described in few case reports. Given the sensitivity o...
