BACKGROUND: This study aimed to develop a novel positron emission tomography (PET) tracer, [68Ga]Ga-TD-01, for CXCR4 imaging. To achieve this goal, the molecular scaffold of TIQ15 was tuned by conjugation with the DOTA chelator to make it suitable for 68Ga radiolabeling. METHODS: A bifunctional chelator was prepared by conjugating the amine group o...
Marcano, David E. Salazar;Marcano, Salazar;Chen, Jieh-Jang;Moussawi, Mhamad Aly; 135548;Kalandia, Givi; 131519;Anyushin, Alexander;Parac-Vogt, Tatjana N.; 37070;
The interactions of polyoxovanadates (POVs) with proteins have increasingly attracted interest in recent years due to their potential biomedical applications. This is especially the case because of their redox and catalytic properties, which make them interesting for developing artificial metalloenzymes. Organic-inorganic hybrid hexavanadates in pa...