The 3 conditions that should be considered in the differential diagnosis of individual ls of predominantly female phenotype who prove to be chromatin negative and 10 have an XY karyotype a re male pseudohermaphrodilism. testicular feminization and gonadal dysgenesis. The clinical finding in the patient reported here suggested the diagnosis of gonad...
Laser irradiated mitochondria in rat myocardial cells were analysed cytochemically for succinic dehydrogenase and with the electron microscope for ultrastructure. The least severe lesion type did not alter the SDH activity of the mitochondria. The major ultrastructural alteration observed was an electron-dense region corresponding to a phase-dark s...
A correlation is made between individual laser microbeam lesions (0.25-1 μm in diameter) in single mitochondria of myocardial cells and alterations in cellular contractility. A moderate lesion is described ultrastructurally that has three concentric zones of damage. In addition, the outer mitochondrial membrane is broken, and the intercristae matri...
Recent studies indicate that right ventricular performance is impaired even in uncomplicated systemic hypertension. Because of widespread use of beta-blockade in essentially hypertension, it is possible that such treatment often further depresses right ventricular contractility. To test this premise, and to evaluate the changes induced by different...
First-pass left ventriculograms were obtained using digital subtraction angiography in 24 patients after intravenous injection of 30 to 40 ml of iodinated contrast material. An image processing computer was used to enhance the iodine signal in the image relative to the background soft tissue by digitizing each new frame of the fluoroscopic exposure...
The ability of pulsed Doppler echocardiography to identify patients with left ventricular systolic dysfunction was evaluated in 12 patients with dilated (congestive) cardiomyopathy. A range-gated, spectrum analyzer-based Doppler velocimeter was used to record blood flow velocity in the ascending aorta and main pulmonary artery. The following blood ...
Using digital subtraction angiography, left ventriculograms were obtained with 10 ml of iodinated contrast material in 21 patients both at rest and during atrial pacing. In 15 patients with significant coronary artery lesions (CAD) (greater than 50% diameter narrowing in at least 1 major artery), ejection fraction decreased during atrial pacing fro...
Erythrocyte deformability was demonstrated to be influenced by platelet activation. Deformability of erythrocytes suspended in autologous platelet poor plasma (PPP), obtained from platelet rich plasma (PRP), was significantly reduced when PRP had previously been incubated with a platelet activating substance (arachidonic acid, adrenaline or ADP). T...
Left ventriculograms were obtained with the use of 10 ml of contrast media by passing fluoroscopic video images through a video image processor. The low concentration of dye in the left ventricle was enhanced by the technique of mask mode subtraction, and the images were postprocessed to increase visibility by manipulation of the gray scale and con...
