Published in The American Journal of Case Reports
Patient: Female, 58-year-old Final Diagnosis: Metastatic amelanotic melanoma Symptoms: Breast mass • breast pain Medication: — Clinical Procedure: Mastectomy Specialty: Dermatology • Oncology Objective: Rare disease Background: Breast metastases from melanoma are rare. Amelanotic melanoma is difficult to diagnose, as primary lesions not only lack t...
Polygenic risk scores (PRS) have been shown to predict breast cancer risk in European women, but their utility in Asian women is unclear. Here we evaluate the best performing PRSs for European-ancestry women using data from 17,262 breast cancer cases and 17,695 controls of Asian ancestry from 13 case-control studies, and 10,255 Chinese women from a...
Responses to immunotherapy are uncommon in estrogen receptor (ER)-positive breast cancer and to date, lack predictive markers. This randomized phase II study defines safety and response rate of epigenetic priming in ER-positive breast cancer patients treated with checkpoint inhibitors as primary endpoints. Secondary and exploratory endpoints includ...
BackgroundOrganophosphate pesticides (OPs) are one of the most commonly used classes of insecticides in the U.S., and metabolites of OPs have been detected in the urine of >75% of the U.S.PopulationWhile studies have shown that OP exposure is associated with risk of neurological diseases and some cancers, the relationship between OP exposure and br...
Response and resistance to anticancer therapies vary due to inter- and intra-tumor heterogeneity. Here, we map differentially enriched G-quadruplex (G4) DNA structure-forming regions (∆G4Rs) in 22 breast cancer patient-derived tumor xenograft (PDTX) models. ∆G4Rs are associated with the promoter of highly amplified and expressed genes, and with som...
Published in Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose Assessing the status of metastasis in sentinel lymph nodes (SLNs) by pathologists is an essential task for the accurate staging of breast cancer. However, histopathological evaluation of SLNs by a pathologist is not easy and is a tedious and time-consuming task. The purpose of this study is to review a challenge competition (HeLP 2018) to d...
Published in Korean journal of family medicine
In recent years, an increased incidence of breast cancer has made this disease the most common malignancy among Iranian women. Since education plays an important role in the implementation of preventive behaviors in breast cancer treatment, this study investigates the effect of educational interventions on the promotion of lifestyle-related behavio...
Published in Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Background The effects of marital status on infiltrating ductal carcinoma of breast cancer (IDC) have not been studied in detail. This study investigated the impact of marital status on IDC patients. Material/Methods SEER databases were searched from 2010 to 2015 for subjects who were married, divorced, single, and widowed. The influence of marital...
