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Styger, Gustav Jacobson, Dan Bauer, Florian F.
Published in
Applied Microbiology and Biotechnology
During alcoholic fermentation, many volatile aroma compounds are formed by Saccharomyces cerevisiae, including esters, fatty acids, and higher alcohols. While the metabolic network that leads to the formation of these compounds is reasonably well mapped, surprisingly little is known about specific enzymes involved in specific reactions, the regulat...
Ward-Caviness, Cavin K. Agha, Golareh Chen, Brian H. Pfeiffer, Liliane Wilson, Rory Wolf, Petra Gieger, Christian Schwartz, Joel Vokonas, Pantel S. Hou, Lifang
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Published in
Clinical Epigenetics
BackgroundMost research into myocardial infarctions (MIs) have focused on preventative efforts. For survivors, the occurrence of an MI represents a major clinical event that can have long-lasting consequences. There has been little to no research into the molecular changes that can occur as a result of an incident MI. Here, we use three cohorts to ...
Bongers, Amaury
La leucémie aiguë myéloïde (LAM) est une hémopathie caractérisée par un blocage de différenciation de progéniteurs/précurseurs myéloïdes. Les mutations affectant les gènes isocitrate déshydrogénase 1 et 2 (IDH1/2), présentes dans 20-25% des LAM, entrainent la production d’un oncométabolite, le D-2- hydroxyglutarate (D-2HG), responsable de perturbat...
Jung, Seungyoun Silva, Sarah Dallal, Cher M LeBlanc, Erin Paris, Kenneth Shepherd, John Snetselaar, Linda G Van Horn, Linda Zhang, Yuji Dorgan, Joanne F
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Published in
Cancer causes & control : CCC
Breast density is an established risk factor for breast cancer. However, little is known about metabolic influences on breast density phenotypes. We conducted untargeted serum metabolomics analyses to identify metabolic signatures associated with breast density phenotypes among young women. In a cross-sectional study of 173 young women aged 25-29 w...