Mastozytosen und myeloische Neoplasien mit Eosinophilie sind seltene Erkrankungen des Knochenmarks und daher oft eine diagnostische Herausforderung für den Hämatopathologen. Bei den Mastozytosen stellen kompakte Mastzellinfiltrate das diagnostische Hauptkriterium dar, bei den myeloischen Neoplasien mit Eosinophilie beherrschen eosinophile Granulozy...
Basic Research in Cardiology
The strategy to reprogram somatic stem cells to pluripotency status has provided an alternative source of surrogate ES cells (ESC). We report efficient reprogramming of multipotent bone marrow (BM) mesenchymal stem cells (MSC) to pluripotent status and the resultant MSC derived iPS cells (MiPS) and their derived progenitors effectively repaired the...
World journal of hepatology
BM progenitor cells do not contribute to fibrosis, but there is a high recruitment of inflammatory cells that stimulates HSCs and MFs of liver origin.
BackgroundWe observed bone marrow signal changes (BMSC) in patients with plexiform neurofibromas after treatment with imatinib mesylate (Gleevec).ObjectiveTo evaluate the pattern and natural history of BMSC.Materials and methodsThe data were obtained from a pilot study of imatinib mesylate in patients with plexiform neurofibromas. All patients unde...
AimLocoregional recurrences and distant metastases in adequately treated head and neck squamous cell carcinoma (HNSCC) patients have a dismal effect on survival. Tumor cells that escape histopathological detection might be the prime cause of this effect. We evaluated whether minimal residual cancer (MRC) in deep surgical margins and disseminated tu...
The migration of neutrophils between tissue compartments is an important aspect of innate immune surveillance. This process is regulated by a cascade of cellular and molecular signals to avoid unnecessary crowding of neutrophils at the periphery, to allow rapid mobilization of neutrophils in response to inflammatory stimuli, and to return to a stat...
Cardiovascular diagnosis and therapy
Chagas disease is caused by a protozoan parasite Trypanosoma cruzi, which infects people through blood sucking insects. It is endemic in Latin America and the disease is being spread to developed countries as a result of the migration of infected individuals. In its chronic stage, Chagas disease can lead to a severe cardiomyopathy for which there i...
Korean journal of audiology
Rat bone marrow-derived MSCs differentiated into neuronal progenitor cells. These cells might be useful for the treatment of SNHL.
Indian Journal of Hematology and Blood Transfusion
Imatinib mesylate (Gleevec) is an effective treatment for chronic myeloid leukemia (CML). Though cytogenetic and molecular analyses are essential disease monitoring parameters in CML bone marrow morphological response is not well defined. We examined marrow samples from 40 patients with CML which have at least 2 or more follow-up marrow. A signific...
Journal of Gastroenterology
BackgroundLymphatic metastasis is a critical determinant of prognosis in human gastrointestinal cancers. Studies suggest that lymphatic metastasis has been linked to lymphangiogenesis, the growth of lymphatic vessels, while the mechanisms of tumor lymphangiogenesis remain poorly characterized.MethodsHuman gastric cancer cells, MKN45, were implanted...