Petrovic, Dusan Marcus, Kailing Sandoval, José Cullati, Stéphane Piumatti, Giovanni Bodenmann, Patrick Jackson, Yves-Laurent Durosier Izart, Claire Wolff, Hans Guessous, Idris
...
Published in
Preventive Medicine Reports
Forgoing healthcare for economic reasons has been previously associated with adverse health outcomes, including a higher risk of hospitalization, a lower quality of life, and worse self-reported health. However, the exact cause-to-effect relation between forgoing healthcare and health-related outcomes has been insufficiently described. Here, we inv...
Sun, Bo Zhang, Bo Guo, Xiang Liu, Wei-Hua Pang, Gui-Fen Yang, Lin-Ying Jiang, Feng Zhang, Qing
Published in
International journal of clinical and experimental pathology
Due to a continued increase in viral pneumonia incidence and resulting high mortality, fast and accurate diagnosis is important for effective management. This investigation examined the significance of blood biomarkers and the CT score in the early diagnosis of viral pneumonia. Patients who were hospitalized due to radiologically-confirmed pneumoni...
Hier, Daniel B. Obafemi-Ajayi, Tayo Thimgan, Matthew S. Olbricht, Gayla R. Azizi, Sima Allen, Blaine Hadi, Bassam A. Wunsch, Donald C. II
Published in
Biomarker Research
BackgroundThe use of blood biomarkers after mild traumatic brain injury (mTBI) has been widely studied. We have identified eight unresolved issues related to the use of five commonly investigated blood biomarkers: neurofilament light chain, ubiquitin carboxy-terminal hydrolase-L1, tau, S100B, and glial acidic fibrillary protein. We conducted a focu...
Moseby-Knappe, Marion Mattsson-Carlgren, Niklas Stammet, Pascal Backman, Sofia Blennow, Kaj Dankiewicz, Josef Friberg, Hans Hassager, Christian Horn, Janneke Kjaergaard, Jesper
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Published in
Intensive Care Medicine
Purpose The majority of unconscious patients after cardiac arrest (CA) do not fulfill guideline criteria for a likely poor outcome, their prognosis is considered “indeterminate”. We compared brain injury markers in blood for prediction of good outcome and for identifying false positive predictions of poor outcome as recommended by guidelines. Metho...
Raabe, Florian J Wagner, Elias Weiser, Judith Brechtel, Sarah Popovic, David Adorjan, Kristina Pogarell, Oliver Hoch, Eva Koller, Gabriele
Published in
European archives of psychiatry and clinical neuroscience
This naturalistic study among patients with alcohol dependence examined whether routine blood biomarkers could help to identify patients with high risk for relapse after withdrawal treatment. In a longitudinal study with 6-month follow-up among 133 patients with alcohol dependence who received inpatient alcohol withdrawal treatment, we investigated...
Banote, Rakesh Kumar Larsson, David Berger, Evelin Kumlien, Eva Zelano, Johan
Published in
Epilepsy research
There is a great need for biomarkers in epilepsy, particularly markers of epileptogenesis. A first seizure will lead to epilepsy in 20-45 % of cases, but biomarkers that can identify these individuals are missing. The purpose of this study was to identify potential biomarkers of epilepsy/epileptogenesis in a cohort of adults with new-onset seizures...
WANG, Peng TANG, Chuanhao LIANG, Jun
Published in
Chinese Journal of Lung Cancer
以免疫检查点抑制剂（immune checkpoint inhibitors, ICI）为代表的免疫治疗改变了非小细胞肺癌（non-small cell lung cancer, NSCLC）的治疗模式，标志物指导下的免疫治疗是精准治疗的关键。基于组织的程序性死亡受体配体1（programmed cell death ligand 1, PD-L1）和肿瘤突变负荷（tumor mutational burden, TMB）是临床上广泛接受的用于指导免疫治疗的生物标志物，然而组织标本不易获取且难以克服肿瘤的时空异质性。外周血标志物作为组织检测的补充，具有取材方便、无创等优势，同时可涵盖肿瘤和宿主免疫状态两方面的信息，在NSCLC免疫治疗疗效预测及治疗反应动态监测方面的价值日益凸显。本文总结NS...
YUE, Shanna L. EKE, Ahizechukwu C. VAIDYA, Dhananjay NORTHINGTON, Frances J. EVERETT, Allen D. GRAHAM, Ernest M.
Published in
Journal of perinatology : official journal of the California Perinatal Association
Biomarkers measured in cord blood at delivery and neonatal serum after birth may identify growth restricted infants at risk for developing severe brain injury.
Broni, Eric K Eke, Ahizechukwu C Vaidya, Dhananjay Tao, Xueting Northington, Frances J Everett, Allen D Graham, Ernest M
Published in
Journal of perinatology : official journal of the California Perinatal Association
To determine if neonatal serum biomarkers representing different pathways of injury differ for cases of HIE of unknown cause to gain insight into timing and mechanism of injury. In this cohort of all neonates with HIE admitted to our NICU, newborns with sentinel events were compared to those without during the 1st 3 days of life. Discard neonatal b...
Jovicic, Snezana M.
Published in
The Journal of Basic and Applied Zoology
BackgroundHomeostasis is a mechanism for maintaining a stable inner environment in healthy participants. Blood and urine biomarkers are indicators of the subject health status. Biomarkers apply for early diagnosis, prognosis, and treatment. Understanding the effect of pre-analytical factors on biomarker range is significant for the data quality of ...
