APAF1 (apoptotic protease activating factor 1)
Review on APAF1 (apoptotic protease activating factor 1), with data on DNA, on the protein encoded, and where the gene is implicated.
In-hospital mortality after resection of biliary tract cancer in the United States
OBJECTIVE: To assess perioperative mortality following resection of biliary tract cancer within the U.S. BACKGROUND: Resection remains the only curative treatment for biliary tract cancer. However, current data on operative mortality after surgical resections for biliary tract cancer are limited to small and single-center studies. METHODS: Using th...
Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits
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Low bone mineral density (BMD) is used as a parameter of osteoporosis. Genome-wide association studies of BMD have hitherto focused on BMD as a quantitative trait, yielding common variants of small effects that contribute to the population diversity in BMD. Here we use BMD as a dichotomous trait, searching for variants that may have a direct effect...
A Meta-Analysis of Gemcitabine Biomarkers in Patients With Pancreaticobiliary Cancers
ObjectivesThe objective of this study was to summarize all clinical studies evaluating the prognostic role of gemcitabine (GEM) metabolic genes in pancreaticobiliary (PB) cancer patients receiving GEM therapy in the neoadjuvant, adjuvant, or palliative settings.MethodsMeta-analyses were performed to calculate the pooled hazard ratios for each gene ...
Inflammatory and metabolic biomarkers and risk of liver and biliary tract cancer
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Obesity and associated metabolic disorders have been implicated in liver carcinogenesis; however, there are little data on the role of obesity-related biomarkers on liver cancer risk. We studied prospectively the association of inflammatory and metabolic biomarkers with risks of hepatocellular carcinoma (HCC), intrahepatic bile duct (IBD), and gall...
Reproductive factors and risk of biliary tract cancer in a population-based study.
The strong female predominance of biliary tract cancer (BTC) may be related to reproductive factors. We aimed to clarify whether parity or age at first birth influence the risk of BTC.This was a population-based, case-control study including Swedish female and male cases of cancer of the gallbladder (GBC), extra hepatic bile ducts (EHCC), or the am...
Reproductive factors and risk of biliary tract cancer in a population-based study.
The strong female predominance of biliary tract cancer (BTC) may be related to reproductive factors. We aimed to clarify whether parity or age at first birth influence the risk of BTC.This was a population-based, case-control study including Swedish female and male cases of cancer of the gallbladder (GBC), extra hepatic bile ducts (EHCC), or the am...
Reproductive factors and risk of biliary tract cancer in a population-based study.
The strong female predominance of biliary tract cancer (BTC) may be related to reproductive factors. We aimed to clarify whether parity or age at first birth influence the risk of BTC.This was a population-based, case-control study including Swedish female and male cases of cancer of the gallbladder (GBC), extra hepatic bile ducts (EHCC), or the am...
Reproductive factors and risk of biliary tract cancer in a population-based study.
The strong female predominance of biliary tract cancer (BTC) may be related to reproductive factors. We aimed to clarify whether parity or age at first birth influence the risk of BTC.This was a population-based, case-control study including Swedish female and male cases of cancer of the gallbladder (GBC), extra hepatic bile ducts (EHCC), or the am...
Reproductive factors and risk of biliary tract cancer in a population-based study
BackgroundThe strong female predominance of biliary tract cancer (BTC) may be related to reproductive factors. We aimed to clarify whether parity or age at first birth influence the risk of BTC.MethodsThis was a population-based, case-control study including Swedish female and male cases of cancer of the gallbladder (GBC), extra hepatic bile ducts ...
