Tosun, Duygu Demir, Zeynep Veitch, Dallas P Weintraub, Daniel Aisen, Paul Jack, Clifford R Jagust, William J Petersen, Ronald C Saykin, Andrew J Shaw, Leslie M
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IntroductionAmyloid beta (Aβ), tau, and neurodegeneration jointly with the Alzheimer's disease (AD) risk factors affect the severity of clinical symptoms and disease progression.MethodsWithin 248 Aβ-positive elderly with and without cognitive impairment and dementia, partial least squares structural equation pathway modeling was used to assess the ...
Marques-Gomes, João Salt, Matthew J Pereira-Neto, Rita Barteldes, Franca S Gouveia-Barros, Vera Carvalho, Alexandre d'Arminio-Monforte, Antonella De-la-Torre-Rosas, Alethse Harris, Amy Esteves, Catarina
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ObjectivesHIV outcomes centre primarily around clinical markers with limited focus on patient-reported outcomes. With a global trend towards capturing the outcomes that matter most to patients, there is agreement that standardizing the definition of value in HIV care is key to their incorporation. This study aims to address the lack of routine, sta...
McMahon, Devon E Singh, Rhea Chemtai, Linda Semeere, Aggrey Byakwaga, Helen Grant, Merridy Laker-Oketta, Miriam Lagat, Celestine Collier, Sigrid Maurer, Toby
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BackgroundKaposi sarcoma is one of the most prevalent HIV-associated malignancies in sub-Saharan Africa and is often diagnosed at advanced stage of disease. Only 50% of KS patients who qualify for chemotherapy receive it and adherence is sub-optimal.Methods57 patients > 18 years with newly diagnosed KS within the AMPATH clinic network in Western Ke...
Harrison, Sayward E Muessig, Kathryn Poteat, Tonia Koester, Kimberly Vecchio, Alyssa Paton, Mariajosé Miller, Sarah J Pereira, Nastacia Harris, Orlando Myers, Janet
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BackgroundRacist socio-political and economic systems in the United States are root causes of HIV disparities among minoritized individuals. However, within HIV implementation science literature, there is scarce empirical research on how to effectively counter racism. This article names racism and White supremacy as key challenges to the success of...
Creel, Sarah C
PurposeThe primary aim was to assess whether children have difficulty distinguishing similar-sounding novel words. The secondary aim was to assess what task characteristics might hinder or facilitate perceptual discrimination.MethodThree within-subjects experiments tested ninety-nine 3- to 5-year-old children total. Experiment 1 presented two carto...
Paolillo, Emily W Saloner, Rowan Kohli, Maulika Watson, C Wei-Ming Moore, Raeanne C Heaton, Robert K Moore, David J
ObjectiveGiven the aging population of people with HIV (PWH), along with increasing rates of binge drinking among both PWH and the general older adult population, this study examined the independent and interactive effects of HIV, binge drinking, and age on neurocognition.MethodParticipants were 146 drinkers stratified by HIV and binge drinking sta...
Solis, Michael Kulesz, Paulina Williams, Kelly
The purpose of this post hoc analysis was to analyze if pre-intervention word reading skills contributed to intervention response on reading comprehension outcomes. High school students with reading difficulties were randomized to a business as usual (BaU) or treatment condition that provided 2 years of an intensive, multicomponent word reading and...
Nishimi, Kristen Borsari, Brian Tripp, Paige Jiha, Ahmad Dolsen, Emily A Woolley, Joshua D Neylan, Thomas C O'Donovan, Aoife
Understanding correlates of COVID-19 vaccine intentions is critical for increasing vaccine uptake. Given associations of trauma exposure and posttraumatic stress disorder (PTSD) with alterations in threat sensitivity and health behaviors, we hypothesized they could influence COVID-19 vaccine acceptance and hesitancy and be important variables to co...
Aknin, Lara B De Neve, Jan-Emmanuel Dunn, Elizabeth W Fancourt, Daisy E Goldberg, Elkhonon Helliwell, John F Jones, Sarah P Karam, Elie Layard, Richard Lyubomirsky, Sonja
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COVID-19 has infected millions of people and upended the lives of most humans on the planet. Researchers from across the psychological sciences have sought to document and investigate the impact of COVID-19 in myriad ways, causing an explosion of research that is broad in scope, varied in methods, and challenging to consolidate. Because policy and ...
Lessard, David Dube, Karine Bilodeau, Martin Keeler, Patrick Margolese, Shari Rosenes, Ron Sinyavskaya, Liliya Durand, Madeleine Benko, Erika Kovacs, Colin
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IntroductionHIV cure research requires interrogating latent HIV reservoirs in deep tissues, which necessitates autopsies to avoid risks to participants. An HIV autopsy biobank would facilitate this research, but such research raises ethical issues and requires participant engagement. This study explores willingness to participate in HIV cure resear...