Sihota, Praveer Yadav, Ram Naresh Poleboina, Sumathi Mehandia, Vishwajeet Bhadada, Sanjay Kumar Tikoo, Kulbhushan Kumar, Navin
Published in
JBMR Plus
Type 2 diabetes (T2D) adversely affects the normal functioning, intrinsic material properties, and structural integrity of many tissues, and bone fragility is one of them. To simulate human T2D and to investigate diabetic bone fragility, many rodent diabetic models have been developed. Still, an outbred genetically normal nonobese diabetic rat mode...
Ross, Ryan D Shah, Raj C Leurgans, Sue E Buchman, Aron S Bennett, David A
Published in
JBMR plus
Age-related bone loss is common in older adults. However, the association of low bone mass with incident disability and mortality is not well established. A sample of 738 participants in the Rush Memory and Aging Project (MAP) was evaluated at baseline for bone mineral density (BMD) using quantitative ultrasound at the calcaneus. An annual intervie...
Onsea, Jolien; 120738; Pallay, Jan; Depypere, Melissa; Moriarty, Thomas Fintan; Van Lieshout, Esther MM; Obremskey, William T; Sermon, An; 41252; Hoekstra, Harm; 97750; Verhofstad, Michael HJ; Nijs, Stefaan; 39354;
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Fracture-related infection (FRI) is a serious complication following musculoskeletal trauma. Accurate diagnosis and appropriate treatment depend on retrieving adequate deep tissue biopsies for bacterial culture. The aim of this cohort study was to compare intraoperative tissue cultures obtained by the Reamer-Irrigator-Aspirator system (RIA)-system ...
Romano, Carlo Luca; Petrosillo, Nicola; Argento, Giuseppe; Sconfienza, Luca Maria; Treglia, Giorgio; Alavi, Abass; Glaudemans, Andor WJM; Gheysens, Olivier; Maes, Alex; 32501; Lauri, Chiara;
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Diagnosing a peri-prosthetic joint infection (PJI) remains challenging despite the availability of a variety of clinical signs, serum and synovial markers, imaging techniques, microbiological and histological findings. Moreover, the one and only true definition of PJI does not exist, which is reflected by the existence of at least six different def...
Williams, Janet L Chung, Wendy K Fedotov, Alex Kiryluk, Krzysztof Weng, Chunhua Connolly, John J Harr, Margaret Hakonarson, Hakon Leppig, Kathleen A Larson, Eric B
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Published in
Healthcare (Basel, Switzerland)
Genomic medicine is moving from research to the clinic. There is a lack of evidence about the impact of genomic medicine interventions on health outcomes. This is due in part to a lack of standardized outcome measures that can be used across different programs to evaluate the impact of interventions targeted to specific genetic conditions. The eMER...
Anthonissen, Joris Steffen, Clara Theressa Alessandri, Beat Baranowski, Andreas Rommens, Pol Maria Victor, Jan Hofmann, Alexander
Published in
Archives of orthopaedic and trauma surgery
The incidence of heterotopic ossification (HO) is at its highest when trauma of the hip or pelvis concurs with traumatic brain injury (TBI). The pathogenic mechanisms underlying the neurogenic enhancement of the formation of HO remain, however, poorly understood. Hence, the goal of the present study was to develop a novel small animal model that co...
Li, Gaoming Zhao, Xiaolong Jia, Xiangwei Li, Shuangqing He, Yongning
Published in
Micromachines
The avalanche photodiode is a highly sensitive photon detector with wide applications in optical communication and single photon detection. ZnO is a promising wide band gap material to realize a UV avalanche photodiode (APD). However, the lack of p-type doping, the strong self-compensation effect, and the scarcity of data on the ionization coeffici...
Chermside-Scabbo, Christopher J Harris, Taylor L Brodt, Michael D Braenne, Ingrid Zhang, Bo Farber, Charles R Silva, Matthew J
Published in
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Mechanical loading is a potent strategy to induce bone formation, but with aging, the bone formation response to the same mechanical stimulus diminishes. Our main objectives were to (i) discover the potential transcriptional differences and (ii) compare the periosteal cell proliferation between tibias of young-adult and old mice in response to stra...
Eeckhout, Célien Bouckaert, Eline Verleyen, Dagmar De Bruyckere, Thomas Cosyn, Jan
Published in
Journal of Clinical Medicine
Background: Xenogeneic soft tissue substitutes are currently being investigated as an alternative to subepithelial connective tissue grafts (CTG) with the intention to avoid postoperative morbidity associated with autologous grafting. The aim of the present study was to volumetrically evaluate the effectiveness and mid-long-term stability of a porc...
Zhang, Jiabin Zhang, Ming Lin, Rongcai Yun, Seonho Du, Yuguang Wang, Liming Yao, Qingqiang Zannettino, Andrew Zhang, Hu
Osteoarthritis (OA) is an inflammation-related chronic disease that causes progressive degeneration of cartilage, which might even extend to subchondral bones. Due to the unique physiological structural differences between cartilage and subchondral bone, it is challenging to restore the full function of an osteochondral defect. In this study, a the...
