Las xilanasas son endoglucanasas capaces de degradar xilano. Estas enzimas se pueden aplicar en varios procesos industriales como en la degradación de residuos agrícolas para obtener azúcares, los cuales se fermentan para producir etanol. La aplicación industrial, sin en embargo, requiere estabilidad principalmente a elevadas temperaturas, por ello...
The pks genomic island of Escherichia coli encodes polyketide (PK) and nonribosomal peptide (NRP) synthases that allow assembly of a putative hybrid PK-NRP compound named colibactin that induces DNA double-strand breaks in eukaryotic cells. The pks-encoded machinery harbors an atypical essential protein, ClbP. ClbP crystal structure and mutagenesis...
Leroux, PierreBach, JocelyneDebieu, DanièleFritz, ReneWalker, Anne Sophie
Sterol biosynthesis inhibitors (SBIs) are major medical and agricultural agents for the control of fungal diseases. According to their respective target sites, four classes can be recognized as inhibitors of: squalene epoxidation, C14-demethylation, Δ 14-reduction and Δ 8 ⃗ Δ 7 - isomerisation, C4- demethylation. The intensive use of SBIs promotes ...
This study investigates whether it is possible to produce an amylose-free potato starch by displacing the amylose enzyme, granule-bound starch synthase I (GBSSI), from the starch granule by engineered, high-affinity, multiple-repeat family 20 starch-binding domains (SBD2, SBD3, SBD4, and SBD5). The constructs were introduced in the amylose-containi...
BackgroundStructural genes of the phenyl-propanoid pathway which encode flavonoid 3'- and 3',5'-hydroxylases (F3'H and F3'5'H) have long been invoked to explain the biosynthesis of cyanidin- and delphinidin-based anthocyanin pigments in the so-called red cultivars of grapevine. The relative proportion of the two types of anthocyanins is largely und...