Weinberg, P Arshad, M Ghim, M Mohamied, Y Sherwin, S

Alignment of arterial endothelial cells with the mean wall shear stress (WSS) vector is the prototypical example of their responsiveness to flow. However, evidence for this behaviour rests on experiments where many WSS metrics had the same orientation or where they were incompletely characterised. In the present study, we tested the phenomenon more...

Mancini, Viviana Bergersen, Aslak W Valen-Sendstad, Kristian Segers, Patrick
Published in
Journal of biomechanical engineering

Early detection of asymptomatic carotid stenosis is crucial for treatment planning in the prevention of ischemic stroke. Auscultation, the current first-line screening methodology, comes with severe limitations that create urge for novel and robust techniques. Laser Doppler vibrometer (LDV) is a promising tool for inferring carotid stenosis by meas...

Lassila, Toni; Sarrami-Foroushani, Ali; Hejazi, SeyedMostafa; Frangi, Alejandro F; 135168;

Computational fluid dynamics models are increasingly proposed for assisting the diagnosis and management of vascular diseases. Ideally, patient-specific flow measurements are used to impose flow boundary conditions. When patient-specific flow measurements are unavailable, mean values of flow measurements across small cohorts are used as normative v...

Mestel, A Mannix, P

In an annular spherical domain with separation d, the onset of convective motion occurs at a critical Rayleigh number Ra = Rac. Solving the linear stability problem, it is shown that degenerate points (d = dc; Rac) exist where two modes simultaneously become unstable. Considering the weakly nonlinear evolution of these modes, it is found that spati...

Wautier, A. Liu, J. Nicot, Frédéric Darve, F.

Plasticity, as induced by continuous irreversible rate‐independent strains, is present in many engineering and natural materials. In this large framework, granular materials play a specific role due to the non‐associated character of their plastic strains. This non‐associativeness is essentially due to a Mohr‐Coulomb plastic limit condition, which ...

Pausch, M Yang, Q Hwang, Y Eckhardt, B

In the quasilinear approximation to the Navier–Stokes equation a minimal set of nonlinearities that is able to maintain turbulent dynamics is kept. For transitional Reynolds numbers, exact coherent structures provide an opportunity for a detailed comparison between full direct numerical solutions of the Navier–Stokes equation with their quasilinear...

Al-Hdaibat, B Govaerts, Willy van Kekem, DL Kuznetsov, YuA

It is known that in the Bogdanov–Takens map there exists a zone of transversal homoclinic intersections bounded by two curves of homoclinic tangencies. In this paper, we derive an improved asymptotic formula for the homoclinic parameter values of the BT map. We compare two methods to approximate the Bogdanov–Takens map by the time-1 flow of a vecto...

Li, Dongchen Turaev, Dmitry V.

We prove that a pair of heterodimensional cycles can be born at the bifurcations of a pair of Shilnikov loops (homoclinic loops to a saddle-focus equilibrium) having a one-dimensional unstable manifold in a volume-hyperbolic flow with a $\mathbb{Z}_2$ symmetry. We also show that these heterodimensional cycles can belong to a chain-transitive attrac...

Boshier, FAT Mestel, AJ

Steady, incompressible flow down a slowly-curving circular pipe is considered, analyti- cally and numerically. Both real and complex solutions are investigated. Using high-order Hermite–Pad ́e approximants, the Dean series solution is analytically continued outside its circle of convergence where it predicts a complex solution branch for real, posi...

Xing, Ruoyu De Wilde, David McCann, Gayle Ridwan, Yanto Schrauwen, Jelle T. C. van der Steen, Anton F. W. Gijsen, Frank J. H. Van der Heiden, Kim
Published in
BioMedical Engineering OnLine

BackgroundWall shear stress (WSS) is involved in the pathophysiology of atherosclerosis. The correlation between WSS and atherosclerosis can be investigated over time using a WSS-manipulated atherosclerotic mouse model. To determine WSS in vivo, detailed 3D geometry of the vessel network is required. However, a protocol to reconstruct 3D murine vas...