Jabłońska, Katarzyna Aballéa, Samuel Auquier, Pascal Toumi, Mondher
Published in
Journal of market access & health policy
This study aims at investigating associations between COVID-19 mortality and SARS-COV-2 variants spread during the second wave of COVID-19 pandemic in Europe. For 38 European countries, data on numbers of COVID-19 deaths, SARS-COV-2 variants spread through time using Nextstrain classification, demographic and health characteristics were collected. ...
Temsah, Mohamad-Hani Barry, Mazin Aljamaan, Fadi Alhuzaimi, Abdullah N. Al-Eyadhy, Ayman Saddik, Basema Alsohime, Fahad Alhaboob, Ali Alhasan, Khalid Alaraj, Ali
...
Published in
Frontiers in Public Health
Background: Healthcare workers' (HCWs') travel-related anxiety needs to be assessed in light of the emergence of SARS-CoV-2 mutations. Methods: An online, cross-sectional questionnaire among HCWs between December 21, 2020 to January 7, 2021. The outcome variables were HCWs' knowledge and awareness of the SARS-CoV-2 B.1.1.7 lineage that was recently...
Arena, Fabio Pollini, Simona Rossolini, Gian Maria Margaglione, Maurizio
Published in
International Journal of Molecular Sciences
Since early 2020, the COVID-19 pandemic has caused an excess in morbidity and mortality rates worldwide. Containment strategies rely firstly on rapid and sensitive laboratory diagnosis, with molecular detection of the viral genome in respiratory samples being the gold standard. The reliability of diagnostic protocols could be affected by SARS-CoV-2...
Lee, Lennard Y W Rozmanowski, Stefan Pang, Matthew Charlett, Andre Anderson, Charlotte Hughes, Gareth J Barnard, Matthew Peto, Leon Vipond, Richard Sienkiewicz, Alex
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Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
How severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectivity varies with viral load is incompletely understood. Whether rapid point-of-care antigen lateral flow devices (LFDs) detect most potential transmission sources despite imperfect clinical sensitivity is unknown. We combined SARS-CoV-2 testing and contact tracing data from Eng...
Yesilkaya, Umit Haluk Sen, Meltem Karamustafalioglu, Nesrin
Published in
Schizophrenia Research
Castonguay, Nicolas Zhang, Wandong Langlois, Marc-André
Published in
Frontiers in Microbiology
Errors are regularly made when SARS-CoV-2 replicates its RNA genome. The viral polymerase complex is error-prone with imperfect proofreading abilities. These errors or mutations often lead to deleterious or neutral effects on the virus. However, sometimes these mutations have a positive effect and create genetic variants of the virus with different...
Chalkias, Athanasios Pantazopoulos, Ioannis Papagiannakis, Nikolaos Skoulakis, Anargyros Laou, Eleni Kolonia, Konstantina Ntalarizou, Nicoletta Tourlakopoulos, Konstantinos Pagonis, Athanasios Kampolis, Christos
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Published in
Toxicology Reports
The progress of COVID-19 from moderate to severe may be precipitous, while the characteristics of the disease are heterogenous. The aim of this study was to describe the development of sinus bradycardia in critically ill patients with COVID-19 and its association with outcome in outbreak due to the SARS-CoV-2 B.1.1.7 Lineage. We leveraged the multi...
Mohammad, Anwar Abubaker, Jehad Al-Mulla, Fahd
Published in
Virus Research
The B.1.1.7 SARS-CoV-2 strain that has emerged in the UK in early December presents seven mutations and three deletions on S-protein structure that could lead to a more infective strain. The P681H mutation in the “PRRAR” furin cleavage site might affect the binding affinity to furin enzyme and hence its infectivity. Therefore, in this study, variou...
Carcereny, Albert Martínez-Velázquez, Adán Bosch, Albert Allende, Ana Truchado, Pilar Cascales, Jenifer Romalde, Jesús L Lois, Marta Polo, David Sánchez, Gloria
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Published in
Environmental science & technology
Since its first identification in the United Kingdom in late 2020, the highly transmissible B.1.1.7 variant of SARS-CoV-2 has become dominant in several countries raising great concern. We developed a duplex real-time RT-qPCR assay to detect, discriminate, and quantitate SARS-CoV-2 variants containing one of its mutation signatures, the ΔHV69/70 de...
Jabłońska, Katarzyna Aballéa, Samuel Toumi, Mondher
Published in
Public Health
Objectives This study aimed at estimating the real-life impact of vaccination on COVID-19 mortality, with adjustment for SARS-CoV-2 variants spread and other factors across Europe and Israel. Study design Time series analysis. Methods Time series analysis of the daily number of COVID-19 deaths was performed using non-linear Poisson mixed regression...
