Fatigue of atherosclerotic plaque
David N. Ku
David N. Ku
Published in Magnetic Resonance Materials in Physics, Biology and Medicine
Published in Studies in Natural Products Chemistry
This article describes physiological properties of two classes of natural products, namely cholesterol oxides and dehydroepiandrosterone (DHEA). The cholesterol oxides, also called oxysterols, are autoxidation products of cholesterol. Dehydroepiandrosterone and its sulfate DHEAS are formed mainly in the adrenals. The biological activities of these ...
Published in Magma: Magnetic Resonance Materials in Physics, Biology, and Medicine
Published in Annals of Biomedical Engineering
Recent advances in molecular and cell biology have emphasized the fundamental importance of mechanical factors in regulating the structure and function of cells and extracellular matrix in the vasculature. Consequently, there is an ever-greater motivation to calculate accurately the stress and strain fields in the arterial wall and how they change ...
INTRODUCTION: The“vulnerable plaque" is defined as the“precursor lesion" that ultimately ends in acute coronary thrombi (clots) that create a heart attack. Macrophages and inflammatory cells, found preferentially in vulnerable plaque, sustain their activity in the plaque through anaerobic metabolism and lactate production. The ultimate goal is to a...
Published in Herz
Mit zunehmender räumlicher und zeitlicher Auflösung hat sich die Magnetresonanztomographie (MRT) im Verlauf der letzten Jahre zu einem viel versprechenden Verfahren zur Bildgebung atherosklerotischer Plaques entwickelt. Die MRT erlaubt neben der Detektion, Volumenbestimmung und Verlaufsbeurteilung atherosklerotischer Plaques auch die Charakterisier...
Published in Cerebrovascular Diseases
Ischaemic strokes and transient ischaemic attacks are commonly caused by cerebral embolism originating from formation of a platelet-rich thrombus superimposed on an atherosclerotic plaque or by atherothrombotic plaque rupture in a carotid or intracranial artery. Despite advances made through ultrasound imaging in our understanding of atheroscleroti...
Published in Inflammation Research
Objective and design: To study changes in the levels of two acute phase proteins, plasma fibrinogen and serum C-reactive protein (hs-CRP) in patients with severe carotid stenosis after eversion endarterectomy. Material and subjects: A total of 117 consecutive patients who underwent eversion endarterectomy were included in the study. Blood samples f...
Published in Surgical and Radiologic Anatomy
The common carotid artery (CCA) bifurcation is of clinical importance due to its vascular access site for intravascular intervention. Additionally, it is also one of the most common sites of atherosclerotic plaque formation. There are numerous studies on the diameters of CCA, internal carotid artery (ICA), and external carotid artery (ECA) in adult...