Hong, Youngtaek Park, Hyung-Bok Lee, Byoung Kwon Ha, Seongmin Jang, Yeonggul Jeon, Byunghwan Jung, Sunghee Shim, Hackjoon Jang, Yang Soo Chang, Hyuk-Jae
...
Published in
European Radiology
ObjectiveThis study aimed to evaluate the clinical feasibility of catheter-directed selective computed tomography angiography (S-CTA) in patients with coronary artery disease (CAD).MethodsWe prospectively enrolled 65 patients diagnosed with CAD who underwent conventional computed tomography angiography (C-CTA). C-CTA was performed with 60–90 mL of ...
Matsumoto, Hidenari Watanabe, Satoshi Kyo, Eisho Tsuji, Takafumi Ando, Yosuke Otaki, Yuka Cadet, Sebastien Gransar, Heidi Berman, Daniel S. Slomka, Piotr
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Published in
European radiology
Objectives We sought to evaluate the accuracy of standardized total plaque volume (TPV) measurement and low-density non-calcified plaque (LDNCP) assessment from coronary CT angiography (CTA) in comparison with intravascular ultrasound (IVUS). Methods We analyzed 118 plaques without extensive calcifications from 77 consecutive patients who underwent...
Park, Myoung Ho Chhai, Pengsrorn Rhee, Kyehan
Published in
International Journal of Precision Engineering and Manufacturing
A novel eccentric stenotic channel was manufactured to provide an in vivo physical environment simulating an atherosclerotic artery. It was composed of an elastic wall containing a soft semi-cylindrical volume that simulated a lipid core. Wall strain and fluid shear stress distributions were computed using a finite element method incorporating flui...
Zareh, Mehrdad Katul, Ramsey Mohammadi, Hadi
Published in
Cardiovascular Engineering and Technology
PurposeAtherosclerotic plaques are highly heterogeneous, nonlinear materials with uncharacteristic structural behaviors. It is well known that mechanics of atherosclerotic plaques significantly depend on plaque geometry, location, composition, and loading conditions. There is no question that atherosclerotic plaques are viscoelastic. Plaques are ch...
Shamloo, Amir Amani, Ali Forouzandehmehr, Mohamadamin Ghoytasi, Ibrahim
Published in
International journal of pharmaceutics
Coronary artery disease is the first cause of death across the world. Targeted delivery of therapeutics through controlled release of micro- and nano-particles remains a very capable approach to develop new strategies in treating restenosis and atherosclerotic plaques. In this research, to produce the arterial geometry, an image-processing was done...
Monteiro, Guilherme Cury, Roberto C. Bittencourt, Marcio S.
Published in
Current Cardiovascular Imaging Reports
Purpose of ReviewThis review addresses the role of serial coronary computed tomography angiography (CTA) on the evaluation of atherosclerosis progression, risk stratification, and targeting individual pharmacotherapy.Recent FindingsThe presence, extent, and severity of coronary artery disease (CAD) detected by coronary CTA are associated with an ad...
Shamloo, Amir Forouzandehmehr, Mohamadamin
Published in
Biomechanics and Modeling in Mechanobiology
Endothelial inflammation as a prominent precursor to atherosclerosis elicits a distinct pathological surface expression of particular vascular proteins. To exhibit a site-specific behaviour, micro- and nanoparticles, as carriers of therapeutics or imaging agents, can distinguish and use these proteins as targeted docking sites. Here, a computationa...
Xu, J. Nie, M. Li, J. Xu, Z. Zhang, M. Yan, Y. Feng, T. Zhao, X. Zhao, Q.
Published in
Herz
BackgroundWe developed an atherosclerotic rabbit model and tested pioglitazone as a drug intervention for early vascular calcification. Positron emission tomography/computed tomography (PET/CT) was used to evaluate inflammation and therapeutic effects.MethodsWe randomly divided 20 male New Zealand white rabbits into a pioglitazone-treated group (n ...
Bucerius, Jan Dijkgraaf, Ingrid Mottaghy, Felix M. Schurgers, Leon J.
Published in
European Journal of Nuclear Medicine and Molecular Imaging
Cardiovascular disease is the major cause of morbidity and mortality in developed countries and atherosclerosis is the major cause of cardiovascular disease. Atherosclerotic lesions obstruct blood flow in the arterial vessel wall and can rupture leading to the formation of occlusive thrombi. Conventional diagnostic tools are still of limited value ...
Vishnu, Abhishek Choo, Jina Kadota, Aya Barinas-Mitchell, Emma J M Fujiyoshi, Akira Long, Dorothy Leann Hisamatsu, Takashi Ahuja, Vasudha Nakamura, Yasuyuki Evans, Rhobert W
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Published in
International journal of cardiology
Carotid plaque has emerged as a marker of coronary heart disease (CHD) risk. Comparison of carotid plaque burden between different race/ethnic groups may provide a relative estimate of their future CHD risk. We conducted a population-based study among apparently healthy middle-aged men aged 40-49 years (ERA JUMP study (n = 924)) and recruited 310 W...
