Developing a placebo-controlled trial in surgery: Issues of design, acceptability and feasibility
10.1186/1745-6215-12-50 / Trials / 12 / 50
Acid-base status and hemodynamic stability during propofol and sevoflurane-based anesthesia in patients undergoing uncom...
peer reviewed / Propofol anesthesia may induce metabolic disturbances and sevoflurane anesthesia arterial hypotension. This study compares both techniques regarding acid-base and hemodynamic status during intracranial surgery. Sixty-one patients were randomized into 2 groups according to anesthesia maintenance, a propofol group (n=30), and a sevofl...
Intra-operative awareness in children and post-traumatic stress disorder
Adults who experience intra-operative awareness can develop disturbing long-lasting after-effects, such as daytime anxiety, sleep disturbances, nightmares, flashbacks and, in the worst case, a post-traumatic stress disorder (PTSD). It is unknown whether intra-operative awareness has a similar psychological impact in children. We designed the presen...
Intra-operative awareness in children: The value of an interview adapted to their cognitive abilities
peer reviewed / Intra-operative awareness in paediatric patients has been little studied for many years because of the difficulties in relying on children's testimony. Earlier questionnaires used to detect this complication were not adapted to children's language and memory capacities. By using a qualitative method, a semi-structured in-depth inter...
A comparison of intubation conditions and time-course of action with rocuronium and mivacurium for day case anaesthesia....
peer reviewed / BACKGROUND AND OBJECTIVE: To compare intubation conditions and time-course of action of rocuronium and mivacurium for day case anaesthesia. METHODS: Fifty ASA I or II patients were enrolled. Anaesthesia was induced with propofol using a target controlled infusion system (target 6-8 microg mL(-1) ) and sufentanil (0.25 microg mL(-1)....
Implantation of electrodes for deep brain stimulation of the subthalamic nucleus in advanced Parkinson's disease with th...
OBJECTIVE: Deep brain stimulation (DBS) is widely accepted in the treatment of advanced Parkinson's disease (PD) and other movement disorders. The standard implantation procedure is performed under local anesthesia (LA). Certain groups of patients may not be eligible for surgery under LA because of clinical reasons, such as massive fear, reduced co...
Comparison of xylazine and medotomidine as premedicants for cats being anaesthetised with propofol-sevoflurane
The effects of premedicating cats with saline, xylazine or medetomidine before anaesthetising them with propofol-sevoflurane were compared. Twenty-four cats were randomly assigned to three groups of eight to receive either 0.25 ml of saline, 0.50 mg/kg of xylazine or 0.02 mg/kg of medetomidine intravenously, and anaesthesia was induced with propofo...
Comparison of xylazine and medotomidine as premedicants for cats being anaesthetised with propofol-sevoflurane
The effects of premedicating cats with saline, xylazine or medetomidine before anaesthetising them with propofol-sevoflurane were compared. Twenty-four cats were randomly assigned to three groups of eight to receive either 0.25 ml of saline, 0.50 mg/kg of xylazine or 0.02 mg/kg of medetomidine intravenously, and anaesthesia was induced with propofo...
Comparison of xylazine and medotomidine as premedicants for cats being anaesthetised with propofol-sevoflurane
The effects of premedicating cats with saline, xylazine or medetomidine before anaesthetising them with propofol-sevoflurane were compared. Twenty-four cats were randomly assigned to three groups of eight to receive either 0.25 ml of saline, 0.50 mg/kg of xylazine or 0.02 mg/kg of medetomidine intravenously, and anaesthesia was induced with propofo...
Comparison of xylazine and medotomidine as premedicants for cats being anaesthetised with propofol-sevoflurane
The effects of premedicating cats with saline, xylazine or medetomidine before anaesthetising them with propofol-sevoflurane were compared. Twenty-four cats were randomly assigned to three groups of eight to receive either 0.25 ml of saline, 0.50 mg/kg of xylazine or 0.02 mg/kg of medetomidine intravenously, and anaesthesia was induced with propofo...
