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General anesthesia with a transcutaneous pacemaker for a Noonan syndrome patient with advanced atrioventricular block di...

Published in Journal of Dental Anesthesia and Pain Medicine

We provided general anesthesia management to a patient with advanced atrioventricular block, which was discovered in the remote period after open-heart surgery. A 21-year-old man with Noonan syndrome was scheduled to undergo excision of a median intramandibular tumor. At 2 months of age, the patient underwent endocardial repair for congenital heart...

Preclinical evidence for anaesthesia-induced neurotoxicity

Preclinical research concerning anaesthesia-induced neurotoxicity was initiated in 1999. A decade later, the earliest clinical observational data showed mixed results in neurodevelopmental outcomes following anaesthesia exposure at a young age. Hence to date, preclinical studies remain the cornerstone of research in this field, primarily because of...

Introduction and history of anaesthesia-induced neurotoxicity and overview of animal models

Brain development is initiated at around 3 weeks of gestation. The peak velocity of brain weight gain occurs around birth, with the neural circuitry subsequently being refined until at least 20 years of age. Antenatal and postnatal general anaesthesia suppresses neuronal firing during this critical period and may therefore impair brain development,...

How we do it: endoscopic tracheal dilatation technique using a supraglottic airway device and non-occlusive balloon.

Published in The Journal of laryngology and otology

Tracheal stenosis can be difficult to manage. Dilatation can relieve acute symptoms, avoid emergency tracheostomy and may be curative, but traditional dilators risk injury and obstruction in an already critical airway. This paper describes a novel technique for conducting tracheobronchial dilatation with a non-occlusive balloon through a supraglott...

Evaluation of dental status using a questionnaire before administration of general anesthesia for the prevention of dent...

Published in Journal of Dental Anesthesia and Pain Medicine

Background Dental evaluation and protection are important for preventing traumatic dental injuries when patients are under general anesthesia. The objective of the present study was to develop a questionnaire based on dentition-related risk factors that could serve as a valuable tool for dental evaluation and documentation. Methods We developed a q...

Type of anaesthesia for acute ischaemic stroke endovascular treatment.

Published in The Cochrane database of systematic reviews

The use of mechanical thrombectomy to restore intracranial blood flow after proximal large artery occlusion by a thrombus has increased over time and led to better outcomes than intravenous thrombolytic therapy alone. Currently, the type of anaesthetic technique during mechanical thrombectomy is under debate as having a relevant impact on neurologi...

FARGO-360: a multi-disciplinary survey of practice and perspectives on provision of care for patients with frailty prese...

Published in International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Frailty has been associated with worse cancer-related outcomes for people with gynecological cancers. However, the lack of clear guidance on how to assess and modify frailty prior to instigating active treatments has the potential to lead to large variations in practice and outcomes. This study aimed to evaluate current practice and perspectives of...

A Cohen syndrome patient whose muscle-relaxant effect may have been prolonged during general anesthesia: a case report

Published in Journal of Dental Anesthesia and Pain Medicine

Cohen syndrome is a rare genetic disorder associated with mutations in the VPS13B gene. Individuals with this disorder present with diverse clinical manifestations, including muscle hypotonia, intellectual disabilities, and typical facial characteristics, such as prominent upper central incisors and micrognathia. General anesthesia was administered...