Metabotropic glutamate receptor 2/3 in the hippocampus of patients with mesial temporal lobe epilepsy, and of rats and m...
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10.1016/j.eplepsyres.2004.04.002 / Epilepsy Research / 59 / 2-3 / 167-180 / EPIRE
10.1016/j.eplepsyres.2004.04.002 / Epilepsy Research / 59 / 2-3 / 167-180 / EPIRE
Published in Naunyn-Schmiedeberg's Archives of Pharmacology
In the mammalian retina, somatostatin (SRIF-14) acts through distinct receptor subtypes (sst1–5). Among them, sst2 has been localized to numerous retinal cells, including photoreceptors and rod bipolar cells (RBCs). The specific role of sst2 in the retina is largely undetermined. In this study, we characterized retinas of mice with targeted deletio...
Published in Archives of Oral Biology
A novel isolated perfused pulpal arteriole preparation and microperfusion system was used to evaluate the direct vasoactive responses of pulpal arterioles to selected agonists. Short lengths of porcine pulpal arterioles (101.7±2.2 μm o.d., n=105) were dissected out and placed in an environment-controlled bath on the stage of an inverted microscope....
Published in Archives of Gynecology and Obstetrics
We report endometrial adenocarcinoma in two patients shortly after suspending GnRH-agonist treatment for menometrorrhagia and uterine fibromata.
Published in Neurosignals
This article reviews our efforts in the development of indole melatonin (MLT) agonist and antagonist compounds. Evidence is presented which indicates that high-affinity melatonergic agonists were obtained by shifting the MLT amido side chain from the C-3 to the N-1 indole position. Conversely, by moving the side chain from the C-3 to the C-2 indole...
The side effects of antibiotics have been extensively described during the last decades, however, their role on digestive motility must be better investigated. Following a line of research, the influence of penicillin, chloranfenicol tetracycline and gentamicine on longitudinal smooth muscle responses to acetylcholine and histamine were studied on ...
Published in Biological Psychiatry
Serotonin 5-HT 2C receptor-mediated intracellular Ca 2+ mobilization was investigated in 5-HT 2C receptors expressed in Chinese hamster ovary (CHO) cells; and fura-2/AM was used to investigate the regulation of 5-HT 2C receptor function. CHO cells, transfected with a cDNA clone for the 5-HT 2C receptor, expressed 287 fmol/mg of the receptor protein...