The total decussation of avian optic tracts offers a system in which biochemical correlates of visual deprivation in one tract can be compared with the opposite tract as a normal control. The short term effect of unilateral eye removal in new hatched chicks was to prevent the normal increases in tissue weight and to modify the level of acetylcholin...
Graduate
Published in Biochemical Pharmacology
Aus'einem Reaktionsansatz mit 5 × 10 −4M Oxim und 2.5 × 10 −6M Soman werden nach einem bestimmten Zeitschema Proben entnommen und die Geschwin-digkeitkonstanten erster Ordnung für die Hemmung von Acetylcholinesterase (EC 3.1.1.7) bestimmt. Aus der zeitlichen Änderung dieser Geschwindigkeitskonstanten lassen sich Aussagen über die Hemmwirkung der ph...
Published in Biochemical and Biophysical Research Communications
Viable synaptosomes from the electric organ of Torpedo have been prepared and partially purified. The synaptosomes contain about 100 fold more acetylcholine (Ach) than do mammalian synaptosomes, synaptic vesicles and mitochondria. The Torpedo synaptosomes release Ach by K depolarization in the presence of Ca ions, and manifest an ionophore-mediated...
Published in Zeitschrift für Naturforschung C
A Cholinesterase deriving from the hemolymph of the mussel Mytilus edulis was partially purified by use of gel-permeation and ion-exchange chromatography; the specifity to different substrates or inhibitors indicates clearly the occurrence of a “true” acetylcholinesterase.
Published in Wilhelm Roux's archives of developmental biology
The developmental accretion of up to nine individual gangliosides in foetal brains, peri- and postnatal cortices, postnatal cerebelli and olfactory lobes and in the liver and the spleen were investigated in mice and compared with that of glycoprotein-bound sialic acid and the activity of the acetylcholinesterase.In foetal brain and in postnatal liv...
Published in Biochemical and Biophysical Research Communications
The release of acetylcholine (Ach) from Torpedo synaptic vesicles has been investigated. Factors have been found which induce Ca +2 dependent Ach release from the synaptic vesicles. In the absence of these factors, the vesicles are not affected by Ca +2. Addition of a soluble factor to the vesicles induces a Ca +2-dependent release of their Ach. Th...
