ENDOCRINE STUDIES OF A NONSTEROID ANTI-ANDROGEN AND PROGESTIN.
Published in Endocrinology
THE INHIBITION OF NICOTINAMIDE-ADENINE DINUCLEOTIDE-LINKED 3-ALPHA-HYDROXY STEROID DEHYDROGENASE BY CERTAIN ANTIMETABOLI...
Published in The Biochemical journal
1. The inhibition of NAD-linked 3alpha-hydroxy steroid dehydrogenase in vitro by some of the more therapeutically effective antimetabolic drugs has been investigated. 2. Antipurine and antifolic acid drugs inhibit this system, as does folic acid. 3. Combinations of antifolic acid drugs and folic acid itself produce an additive but not synergic inhi...
THE EFFECT OF DISULPHIDES ON MITOCHONDRIAL OXIDATIONS.
Published in The Biochemical journal
1. Nicotinamide nucleotide-linked mitochondrial oxidations were inhibited by the disulphides NNN'N'-tetraethylcystamine, cystamine and cystine diethyl ester, whereas l-homocystine, oxidized mercaptoethanol, oxidized glutathione, NN'-diacetylcystamine and tetrathionate were only slightly inhibitory. Mitochondrial oxidations were not blocked by the t...
INHIBITION OF HEXOSE AND GLYCEROL UTILIZATION BY 2-DEOXY-D-GLUCOSE IN TRYPANOSOMA GAMBIENSE AND TRYPANOSOMA RHODESIENSE....
Published in Experimental parasitology
COMPARISON OF THE EFFECTS OF SOME RADIATION MODIFIERS ON SELECTED RADIOMIMETIC AGENTS IN MICROORGANISMS.
Published in Radiation research
FURTHER OBSERVATIONS ON THE PRODUCTION OF AMINO ACIDS BY RAT-LIVER MITOCHONDRIA AND OTHER SUBCELLULAR FRACTIONS.
Published in The Biochemical journal
1. Rat-liver mitochondria showed a decrease in amino acid production after preparation in 0.25m-sucrose containing EDTA (1mm), but an increase in water content. When EDTA was replaced by Mn(2+) (1mm) or succinate (1mm), both amino acid production and water content were lowered, whereas preparation in 0.9% potassium chloride caused an increase in bo...
DIFFERENTIAL EFFECTS OF INHIBITORS ON THE STEPS LEADING TO THE FORMATION OF SV40 TUMOR AND VIRUS ANTIGENS.
Published in The Journal of experimental medicine
The effect of DNA antagonists and various antibiotics on steps in the synthesis of SV40 virus in green monkey kidney cells was investigated. Both the early forming tumor (T) antigen, as well as the later synthesized virus (V) antigen, were synthesized in the presence of fluorouracil and iododeoxyuridine. Cytosine arabinoside (and fluorodeoxyuridine...
THE EFFECT OF PUROMYCIN AND ACTINOMICIN D ON THE DEVELOPMENT OF GRASSHOPPER FLIGHT MUSCLE GLYCEROLPHOSPHATE DEHYDROGENAS...
Published in Biochimica et biophysica acta
A CASE OF DERMATOMYOSITIS TREATED WITH 6-MERCAPTOPURINE AND AZATHIOPRINE.
Published in The Medical journal of Australia
STUDIES IN PURINE CHEMISTRY. 13. SYNTHESIS OF THE 5-AZA ANALOGS OF ADENINE AND HYPOXANTHINE.
Published in Journal of the American Chemical Society
