The aim of the study was to investigate the time of onset and the duration of the bronchodilating effect of different doses of formoterol administered via Tulbuhaler(R) in patients with moderate asthma. Thirty-one patients (five women) with a mean forced expiratory volume in s (FEV1) of 1.97 +/- 0.541 and a mean reversibility of 31 +/- 14% of basel...
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SIGLE / Available from British Library Document Supply Centre-DSC:DXN032967 / BLDSC - British Library Document Supply Centre / GB / United Kingdom
平成13-15年度科学研究費補助金(基盤研究(B)(2))研究成果報告書 課題番号：13460058 研究代表者：河田照雄 (京都大学大学院農学研究科 教授)
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Lipid accumulation in nonadipose tissues is increasingly linked to the development of type 2 diabetes in obese individuals. We report here the design, synthesis, and evaluation of a series of novel PPARalpha selective activators containing 1,3-dicarbonyl moieties. Structure-activity relationship studies led to the identification of PPARalpha select...