Notter, Tina Coughlin, J M Sawa, A Meyer, Urs
A great deal of interest in psychiatric research is currently centered upon the pathogenic role of inflammatory processes. Positron emission tomography (PET) using radiolabeled ligands selective for the 18 kDa translocator protein (TSPO) has become the most widely used technique to assess putative neuroimmune abnormalities in vivo. Originally used ...
Arand, Michael Marowsky, Anne
Epoxide hydrolases (EHs) metabolize highly reactive epoxides with mutagenic and carcinogenic potential to the less reactive corresponding diols and are therefore traditionally viewed as detoxicating enzymes. In few instances, however, the diols themselves can be precursors of further reactive metabolites, and EH may thereby contribute to metabolic ...
Notter, Tina Coughlin, J M Sawa, A Meyer, Urs
A great deal of interest in psychiatric research is currently centered upon the pathogenic role of inflammatory processes. Positron emission tomography (PET) using radiolabeled ligands selective for the 18 kDa translocator protein (TSPO) has become the most widely used technique to assess putative neuroimmune abnormalities in vivo. Originally used ...
Personnic, Nicolas Striednig, Bianca Hilbi, Hubert
Legionella pneumophila is a water-borne opportunistic pathogen causing a life-threatening pneumonia called 'Legionnaires' disease'. The Legionella quorum sensing (Lqs) system produces and responds to the α-hydroxyketone signaling molecule 3-hydroxypentadecane-4-one (Legionella autoinducer-1, LAI-1). The Lqs system controls the switch between the re...
Personnic, Nicolas Striednig, Bianca Hilbi, Hubert
Legionella pneumophila is a water-borne opportunistic pathogen causing a life-threatening pneumonia called 'Legionnaires' disease'. The Legionella quorum sensing (Lqs) system produces and responds to the α-hydroxyketone signaling molecule 3-hydroxypentadecane-4-one (Legionella autoinducer-1, LAI-1). The Lqs system controls the switch between the re...
Personnic, Nicolas Striednig, Bianca Hilbi, Hubert
Legionella pneumophila is a water-borne opportunistic pathogen causing a life-threatening pneumonia called 'Legionnaires' disease'. The Legionella quorum sensing (Lqs) system produces and responds to the α-hydroxyketone signaling molecule 3-hydroxypentadecane-4-one (Legionella autoinducer-1, LAI-1). The Lqs system controls the switch between the re...
Deliu, Elena Arecco, Niccolò Morandell, Jasmin Dotter, Christoph P Contreras, Ximena Girardot, Charles Käsper, Eva-Lotta Kozlova, Alena Kishi, Kasumi Chiaradia, Ilaria
...
SETD5 gene mutations have been identified as a frequent cause of idiopathic intellectual disability. Here we show that Setd5-haploinsufficient mice present developmental defects such as abnormal brain-to-body weight ratios and neural crest defect-associated phenotypes. Furthermore, Setd5-mutant mice show impairments in cognitive tasks, enhanced lon...
Deliu, Elena Arecco, Niccolò Morandell, Jasmin Dotter, Christoph P Contreras, Ximena Girardot, Charles Käsper, Eva-Lotta Kozlova, Alena Kishi, Kasumi Chiaradia, Ilaria
...
SETD5 gene mutations have been identified as a frequent cause of idiopathic intellectual disability. Here we show that Setd5-haploinsufficient mice present developmental defects such as abnormal brain-to-body weight ratios and neural crest defect-associated phenotypes. Furthermore, Setd5-mutant mice show impairments in cognitive tasks, enhanced lon...
Deliu, Elena Arecco, Niccolò Morandell, Jasmin Dotter, Christoph P Contreras, Ximena Girardot, Charles Käsper, Eva-Lotta Kozlova, Alena Kishi, Kasumi Chiaradia, Ilaria
...
SETD5 gene mutations have been identified as a frequent cause of idiopathic intellectual disability. Here we show that Setd5-haploinsufficient mice present developmental defects such as abnormal brain-to-body weight ratios and neural crest defect-associated phenotypes. Furthermore, Setd5-mutant mice show impairments in cognitive tasks, enhanced lon...
Deliu, Elena Arecco, Niccolò Morandell, Jasmin Dotter, Christoph P Contreras, Ximena Girardot, Charles Käsper, Eva-Lotta Kozlova, Alena Kishi, Kasumi Chiaradia, Ilaria
...
SETD5 gene mutations have been identified as a frequent cause of idiopathic intellectual disability. Here we show that Setd5-haploinsufficient mice present developmental defects such as abnormal brain-to-body weight ratios and neural crest defect-associated phenotypes. Furthermore, Setd5-mutant mice show impairments in cognitive tasks, enhanced lon...