Itch Is More Important than Clinical Disease Severity for Depression in Psoriasis: A Prospective Register Study.
Published in The Journal of investigative dermatology
Itch Is More Important than Clinical Disease Severity for Depression in Psoriasis: A Prospective Register Study.
FOXE1 Contributes to the Development of Psoriasis by Regulating WNT5A.
...Published in The Journal of investigative dermatology
Psoriasis is a common, chronic, and relapsing inflammatory skin disease characterized by hyperproliferation of keratinocytes (KCs) and infiltration of immune cells. The pathogenesis of psoriasis is complex, and the exact mechanism remains partially understood. In this study, we showed that the forkhead box family protein, FOXE1, had increased expre...
Antifungal Resistance on the Rise.
Published in The Journal of investigative dermatology
Skin Barrier Fine Tuning through Low-Temperature Lipid Chain Transition.
Published in The Journal of investigative dermatology
The lipids in the mammalian stratum corneum (SC) adopt an unusually rigid arrangement to form a vital barrier preventing water loss and harmful environmental impacts. Just above the physiological temperature, a subset of barrier lipids undergoes a phase transition from a very tight orthorhombic to a looser hexagonal arrangement and vice versa. The ...
Correspondence Concerning PTPN11 Mosaicism Causes a Spectrum of Pigmentary and Vascular Neurocutaneous Disorders and Pre...
Published in The Journal of investigative dermatology
PD-1 Overexpression in Sézary Syndrome Is Epigenetically Regulated.
Published in The Journal of investigative dermatology
Detection of Squalene Epoxidase Mutations in United States Patients with Onychomycosis: Implications for Management.
Published in The Journal of investigative dermatology
Resistance to oral terbinafine, the most commonly used antifungal to treat dermatophytosis and onychomycosis worldwide, is being increasingly reported. In this study, we aimed to investigate the species distribution and prevalence of squalene epoxidase mutations among toenail dermatophyte isolates. Samples from 15,683 patients suspected of onychomy...
MicroRNA-23b Plays a Tumor-Suppressive Role in Cutaneous Squamous Cell Carcinoma and Targets Ras-Related Protein RRAS2.
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Published in The Journal of investigative dermatology
Cutaneous squamous cell carcinoma (cSCC) is one of the most common types of cancer with metastatic potential. MicroRNAs regulate gene expression at the post-transcriptional level. In this study, we report that miR-23b is downregulated in cSCCs and in actinic keratosis and that its expression is regulated by the MAPK signaling pathway. We show that ...
In-Hospital Clinical Features, Morbidity, and Mortality of Patients with Neurofibromatosis 1 in France: A Nationwide, Po...
...Published in The Journal of investigative dermatology
Neurofibromatosis 1 (NF1) is a multisystem disease that can affect nearly every organ system. The aim of our study was to describe the in-hospital population with NF1 in France. We conducted a nationwide retrospective cohort study using the French hospital administrative database. A total of 11,425 patients with NF1 (53.4% female, 19,080 person yea...
Response to Torchia.
Published in The Journal of investigative dermatology
