Meyts, Isabelle Bucciol, Giorgia Quinti, Isabella Neven, Bénédicte Fischer, Alain Seoane, Elena Lopez-Granados, Eduardo Gianelli, Carla Robles-Marhuenda, Angel Jeandel, Pierre-Yves
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Published in
The Journal of allergy and clinical immunology
There is uncertainty about the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in individuals with rare inborn errors of immunity (IEI), a population at risk of developing severe coronavirus disease 2019. This is relevant not only for these patients but also for the general population, because studies of IEIs can un...
Abraham, Roshini S Marshall, Joanna M Kuehn, Hye Sun Rueda, Cesar M Gibbs, Amber Guider, Will Stewart, Claire Rosenzweig, Sergio D Wang, Huanyu Jean, Sophonie
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Published in
The Journal of allergy and clinical immunology
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus that emerged recently and has created a global pandemic. Symptomatic SARS-CoV-2 infection, termed coronavirus disease 2019 (COVID-19), has been associated with a host of symptoms affecting numerous organ systems, including the lungs, cardiovascular system, kidney, c...
Finney, Lydia J Glanville, Nicholas Farne, Hugo Aniscenko, Julia Fenwick, Peter Kemp, Samuel V Trujillo-Torralbo, Maria-Belen Loo, Su Ling Calderazzo, Maria Adelaide Wedzicha, Jadwiga A
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Published in
The Journal of allergy and clinical immunology
The mechanisms underlying altered susceptibility and propensity to severe Coronavirus disease 2019 (COVID-19) disease in at-risk groups such as patients with chronic obstructive pulmonary disease (COPD) are poorly understood. Inhaled corticosteroids (ICSs) are widely used in COPD, but the extent to which these therapies protect or expose patients t...
Stevens, Whitney W Staudacher, Anna G Hulse, Kathryn E Carter, Roderick G Winter, Deborah R Abdala-Valencia, Hiam Kato, Atsushi Suh, Lydia Norton, James E Huang, Julia H
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Published in
The Journal of allergy and clinical immunology
Aspirin-exacerbated respiratory disease (AERD) is characterized by asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), and an intolerance of medications that inhibit cyclooxygenase-1. Patients with AERD have more severe upper and lower respiratory tract disease than do aspirin-tolerant patients with CRSwNP. A dysregulation in arachidonic aci...
Smeekens, Johanna M Immormino, Robert M Kulis, Michael D Moran, Timothy P
Published in
The Journal of allergy and clinical immunology
Melén, Erik Standl, Marie Gehring, Ulrike Altug, Hicran Antó, Josep Maria Berdel, Dietrich Bergström, Anna Bousquet, Jean Heinrich, Joachim Koppelman, Gerard H
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Published in
The Journal of allergy and clinical immunology
Whether long-term exposure air to pollution has effects on allergic sensitization is controversial. Our aim was to investigate associations of air pollution exposure at birth and at the time of later biosampling with IgE sensitization against common food and inhalant allergens, or specific allergen molecules, in children aged up to 16 years. A tota...
Scurlock, Amy M Burks, A Wesley Sicherer, Scott H Leung, Donald Y M Kim, Edwin H Henning, Alice K Dawson, Peter Lindblad, Robert W Berin, M Cecilia Cho, Christine B
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Published in
The Journal of allergy and clinical immunology
CoFAR investigators previously reported 52-week outcomes from a randomized, controlled trial of peanut EPIT, observing modest and statistically significant induction of desensitization, highest in children ages 4-11 years. To evaluate changes in efficacy, safety, and mechanistic parameters following extended open-label peanut EPIT. Peanut-allergic ...
Stevens, Mariana L Gonzalez, Tammy Schauberger, Eric Baatyrbek Kyzy, Asel Andersen, Heidi Spagna, Daniel Kalra, Mehak K Martin, Lisa J Haslam, David Herr, Andrew B
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Published in
The Journal of allergy and clinical immunology
Rastogi, Shruti Willmes, Diana Maria Nassiri, Maria Babina, Magda Worm, Margitta
Published in
The Journal of allergy and clinical immunology
Reduced levels of prostaglandin E2 (PGE2) contribute to aspirin-induced hypersensitivity. COX inhibitors are also frequent cofactors in anaphylaxis. Whether alterations in the PGE2 system contribute to anaphylaxis independently of COX inhibitor intake is unclear. Our aim was to test the hypothesis that relative PGE2 deficiency predisposes to anaphy...
Ownby, Dennis R Havstad, Suzanne Wegienka, Ganesa Johnson, Christine C
Published in
The Journal of allergy and clinical immunology
