Hopkins, Peter M Plit, Marshall L Carter, Ian W Chhajed, Prashant N Malouf, Monique A Glanville, Allan R
Published in
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
Rapid and reliable diagnosis of respiratory viral infections (RVI) in lung transplant recipients is essential to direct therapy of acute graft dysfunction and identify epidemic trends. Traditional techniques of serology and viral culture are limited by the lack of antibody response and delay in diagnosis. We examined the clinical utility of indirec...
Garrity, Edward R Jr Boettcher, Heidi Gabbay, Eli
Published in
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
Humar, Atul Doucette, Karen Kumar, Deepali Pang, Xiao-Li Lien, Dale Jackson, Kathy Preiksaitis, Jutta
Published in
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
Little is known about adenovirus infections in adult lung transplant recipients. Because the virus can establish latency, re-activation may be relatively common after transplantation. We assessed adenovirus infection in 80 adult lung transplant recipients. Adenovirus polymerase chain reaction (real-time PCR assay; limit of detection approximately 2...
Raza, Kashif Ismailjee, Sameer B Crespo, Maria Studer, Sean M Sanghavi, Sonali Paterson, David L Kwak, Eun J Rinaldo, Charles R Jr Pilewski, Joseph M McCurry, Kenneth R
...
Published in
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
Human metapneumovirus (hMPV) has recently been shown to be a prominent cause of respiratory infections in immunocompromised hosts, and is associated with high morbidity and mortality. We report a case of hMPV pneumonia in a lung transplant recipient presenting with respiratory failure and sepsis syndrome. hMPV was diagnosed by polymerase chain reac...
Roussel, Jean C Baron, Olivier Périgaud, Christian Bizouarn, Philippe Pattier, Sabine Habash, Oussama Mugniot, Antoine Petit, Thierry Michaud, Jean L Heymann, Marie Françoise
...
Published in
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
Long-term survival at 15 years after cardiac transplantation remains excellent in the cyclosporine era. Controlling acute allograft rejection can be achieved but seems to carry a high rate of cancers and renal dysfunction. History of cigarette use affects significantly long-term survival in our study.
Knight, Jennifer Elwing, Jean M Milstone, Aaron
Published in
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
Although most late complications after lung transplantation are related to chronic rejection, airway anastomotic disease cannot be overlooked as a substantial contributor to morbidity and mortality. A rare, but nearly universally fatal example of anastomotic disease is fistula formation with the vascular system. Reports of fistula formation between...
Miyagi, Naoto Rao, Vinay P Ricci, Davide Du, Zeji Byrne, Guerard W Bailey, Kent R Nakai, Hiroyuki Russell, Stephen J McGregor, Christopher G A
Published in
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
Our findings demonstrate efficient and durable rAAV9-mediated gene transfer to the transplanted heart after ex vivo perfusion and suggest that AAV9 is a promising vector for cardiac gene therapy.
Halsey, Kevin D Wald, Arnold Meyer, Keith C Torrealba, Jose R Gaumnitz, Eric A
Published in
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
Advances in lung transplantation have improved 1-year survival rates, but allograft dysfunction continues to be a significant cause of post-transplant death. Diffuse alveolar damage is an early indication of allograft dysfunction and has been linked to gastroesophageal reflux. We report a case of diffuse alveolar damage-associated allograft dysfunc...
Schubert, Stephan Abdul-Khaliq, Hashim Wellnhofer, Ernst Hiemann, Nicola Erika Ewert, Peter Lehmkuhl, Hans Brendan Meyer, Rudolf Miera, Oliver Peters, Bjoern Hetzer, Roland
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Published in
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
CFR and coronary vasoreactivity to adenosine are decreased in pediatric patients with CAV and correlate with histopathologic and angiographic evidence of microvascular disease. Measurement of CFR with intracoronary and systemic application of adenosine is comparable, while systemic application is necessary for non-invasive measurement of CFR in ped...
Kaufman, Beth D Nagle, Monica L Levine, Selena R Vijaynathan, Nirmala Hanna, Brian D Paridon, Stephen Ravishankar, Chitra Chrisant, Maryanne K
Published in
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
Abnormal BHA at listing was a prognostic factor for survival post-transplant. Obese children had increased mortality, but wasting did not adversely affect post-transplant survival in our population. Body habitus assessment may risk-stratify children at listing, potentially providing a complex target for intervention.