Presland, Joel D Tofari, Paul J Timmins, Ryan G Kidgell, Dawson J Opar, David A
Published in
The European journal of neuroscience
This study aimed to determine the test-retest reliability of a range of transcranial magnetic stimulation (TMS) outcomes in the biceps femoris during isometric, eccentric and concentric contractions. Corticospinal excitability (active motor threshold 120% [AMT120%] and area under recruitment curve [AURC]), short- and long-interval intracortical inh...
Al-Onaizi, Mohammed Al-Sarraf, Ahmad Braysh, Kawthar Kazem, Fatema Al-Hussaini, Heba Rao, Muddanna Kilarkaje, Narayana ElAli, Ayman
Published in
The European journal of neuroscience
Type 2 diabetes mellitus (T2DM) increases the risk of developing Alzheimer's disease (AD), which has been proposed to be driven by an abnormal neuroinflammatory response affecting cognitive function. However, the impact of T2DM on hippocampal function and synaptic integrity during aging has not been investigated. Here, we investigated the effects o...
Dias, James W McClaskey, Carolyn M Rumschlag, Jeffrey A Harris, Kelly C
Published in
The European journal of neuroscience
There is great interest in developing non-invasive approaches for studying cortical plasticity in humans. High-frequency presentation of auditory and visual stimuli, or sensory tetanisation, can induce long-term-potentiation-like (LTP-like) changes in cortical activity. However, contrasting effects across studies suggest that sensory tetanisation m...
Al-Asmar, Alid Pérez-Escudero, Alfonso
Published in
The European journal of neuroscience
Grignolio, Andrea Morelli, Micaela Tamietto, Marco
Published in
The European journal of neuroscience
Sugisaki, Eriko Fukushima, Yasuhiro Nakajima, Naoki Aihara, Takeshi
Published in
The European journal of neuroscience
The hippocampus is an important area for memory encoding and retrieval and is the location of spike timing-dependent plasticity (STDP), a basic phenomenon of learning and memory. STDP is facilitated if acetylcholine (ACh) is released from cholinergic neurons during attentional processes. However, it is unclear how ACh influences postsynaptic change...
Öztekin, Ilke Garic, Dea Bayat, Mohammadreza Hernandez, Melissa L Finlayson, Mark A Graziano, Paulo A Dick, Anthony Steven
Published in
The European journal of neuroscience
The current study aimed to identify the key neurobiology of attention-deficit/hyperactivity disorder (ADHD), as it relates to ADHD diagnostic category and symptoms of hyperactive/impulsive behaviour and inattention. To do so, we adapted a predictive modelling approach to identify the key structural and diffusion-weighted brain imaging measures and ...
Animali, Silvia Steinwurzel, Cecilia Dardano, Angela Sancho-Bornez, Veronica Del Prato, Stefano Morrone, Maria Concetta Daniele, Giuseppe Binda, Paola
Published in
The European journal of neuroscience
Brain plasticity and function is impaired in conditions of metabolic dysregulation, such as obesity. Less is known on whether brain function is also affected by transient and physiological metabolic changes, such as the alternation between fasting and fed state. Here we asked whether these changes affect the transient shift of ocular dominance that...
Stevenson, Anna J McCartney, Daniel L Gadd, Danni A Shireby, Gemma Hillary, Robert F King, Declan Tzioras, Makis Wrobel, Nicola McCafferty, Sarah Murphy, Lee
...
Published in
The European journal of neuroscience
Inflammation and ageing-related DNA methylation patterns in the blood have been linked to a variety of morbidities, including cognitive decline and neurodegenerative disease. However, it is unclear how these blood-based patterns relate to patterns within the brain and how each associates with central cellular profiles. In this study, we profiled DN...
Steele, Oliver George Stuart, Alexander Cameron Minkley, Lucy Shaw, Kira Bonnar, Orla Anderle, Silvia Penn, Andrew Charles Rusted, Jennifer Serpell, Louise Hall, Catherine
...
Published in
The European journal of neuroscience
The APOE gene encoding the Apolipoprotein E protein is the single most significant genetic risk factor for late-onset Alzheimer's disease. The APOE4 genotype confers a significantly increased risk relative to the other two common genotypes APOE3 and APOE2. Intriguingly, APOE4 has been associated with neuropathological and cognitive deficits in the ...
