Rodrigues, Filipe B Byrne, Lauren M De Vita, Enrico Johnson, Eileanoir B Hobbs, Nicola Z Thornton, John S Scahill, Rachael I Wild, Edward J
Published in
The European journal of neuroscience
Multiple targeted therapeutics for Huntington's disease are now in clinical trials, including intrathecally delivered compounds. Previous research suggests that CSF dynamics may be altered in Huntington's disease, which could be of paramount relevance to intrathecal drug delivery to the brain. To test this hypothesis, we conducted a prospective cro...
Whitehead, Jocelyne C Armony, Jorge L
Published in
The European journal of neuroscience
The emotional expression of fear can be processed through a number of modalities, and of varying forms, however, much of the functional imaging literature has centered on investigating fear as expressed through faces. Findings point to an active involvement of the amygdala, and remain fairly consistent in other studies of unimodal fear perception; ...
Körner, Sonja Thau-Habermann, Nadine Kefalakes, Ekaterini Bursch, Franziska Petri, Susanne
Published in
The European journal of neuroscience
Amyotrophic Lateral Sclerosis (ALS) is a degenerative motor neuron disorder. It is supposed that ALS is at least in part an axonopathy. Neuropilin 1 is an important receptor of the axon repellent Semaphorin 3A and a co-receptor of vascular endothelial growth factor. It is probably involved in neuronal and axonal de-/regeneration and might be of hig...
Lo, On-Yee van Donkelaar, Paul Chou, Li-Shan
Published in
The European journal of neuroscience
Attention involves three distinct networks for alerting, orienting, and executive control. Interventions targeting the specific attentional networks remain lacking. Transcranial direct current stimulation (tDCS) has been shown to modulate cortical excitability, which potentially serves as an interventional tool to treat individuals with attention i...
Coggan, David D Baker, Daniel H Andrews, Timothy J
Published in
The European journal of neuroscience
Regions in the ventral visual pathway, such as the fusiform face area (FFA) and parahippocampal place area (PPA) are selective for images from specific object categories. Yet images from different object categories differ in their image properties. To investigate how these image properties are represented in the FFA and PPA, we compared neural resp...
Rogers, Mags Boland, Barry Clarke, Sarah Craven, Audrey Fassbender, Catherine Gill, Michael Hardiman, Orla Henshall, David C Lynch, Tim Mitchell, Kevin
...
Published in
The European journal of neuroscience
Bastos, André E P Costa, Pedro F Varderidou-Minasian, Suzy Altelaar, Maarten Lima, Pedro A
Published in
The European journal of neuroscience
The function of hippocampus as a hub for energy balance is a subject of broad and current interest. This study aims at providing more evidence on this regard by addressing the effects of feeding cycle on the voltage-gated sodium (Na+ ) currents of acutely isolated Wistar rat hippocampal CA1 neurones. Specifically, by applying patch clamp techniques...
Jáidar, Omar Carrillo-Reid, Luis Nakano, Yoko Lopez-Huerta, Violeta Gisselle Hernandez-Cruz, Arturo Bargas, José Garcia-Munoz, Marianela Arbuthnott, Gordon William
Published in
The European journal of neuroscience
For more than three decades it has been known, that striatal neurons become hyperactive after the loss of dopamine input, but the involvement of dopamine (DA) D1- or D2-receptor-expressing neurons has only been demonstrated indirectly. By recording neuronal activity using fluorescent calcium indicators in D1 or D2 eGFP-expressing mice, we showed th...
Iida, Tadatsune Tanaka, Shinji Okabe, Shigeo
Published in
The European journal of neuroscience
Microglia regulate synapse stability and remodeling through multiple molecular pathways. Regulated spatial distribution of microglia within nervous tissues may affect synapse dynamics. Here, we focused on the spatial relationship between microglia and spine synapses in the mouse neocortex and found that the distance between microglial cell bodies (...
Papo, David
Published in
The European journal of neuroscience
Neurofeedback is a form of brain training in which subjects are fed back information about some measure of their brain activity which they are instructed to modify in a way thought to be functionally advantageous. Over the last 20 years, neurofeedback has been used to treat various neurological and psychiatric conditions, and to improve cognitive f...
