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Opposing activities of IFITM proteins in SARS‐CoV‐2 infection

Shi, Guoli Kenney, Adam D. Kudryashova, Elena Zani, Ashley Zhang, Lizhi Lai, Kin Kui Hall‐Stoodley, Luanne Robinson, Richard T. Kudryashov, Dmitri S. Compton, Alex A. ...

Published in The EMBO Journal

Interferon‐induced transmembrane proteins (IFITMs) restrict infections by many viruses, but a subset of IFITMs enhance infections by specific coronaviruses through currently unknown mechanisms. We show that SARS‐CoV‐2 Spike‐pseudotyped virus and genuine SARS‐CoV‐2 infections are generally restricted by human and mouse IFITM1, IFITM2, and IFITM3, us...

LRRK 2 regulates endoplasmic reticulum–mitochondrial tethering through the PERK ‐mediated ubiquitination pathway

Toyofuku, Toshihiko Okamoto, Yuki Ishikawa, Takako Sasawatari, Shigemi Kumanogoh, Atsushi

Published in The EMBO Journal

Optimal sidestepping of intraflagellar transport kinesins regulates structure and function of sensory cilia

Xie, Chao Li, Liuju Li, Ming Shao, Wenxin Zuo, Qingyu Huang, Xiaoshuai Chen, Riwang Li, Wei Brunnbauer, Melanie Ökten, Zeynep ...

Published in The EMBO Journal

α‐Actinin‐1 promotes activity of the L‐type Ca 2+ channel Ca v1.2

Turner, Matthew Anderson, David E Bartels, Peter Nieves‐Cintron, Madeline Coleman, Andrea M Henderson, Peter B Man, Kwun Nok Mimi Tseng, Pang‐Yen Yarov‐Yarovoy, Vladimir Bers, Donald M ...

Published in The EMBO Journal

Domain structure of secretin PulD revealed by limited proteolysis and electron microscopy.

Nouwen, N Stahlberg, H Pugsley, A P Engel, A

Published in The EMBO journal

Secretins, a superfamily of multimeric outer membrane proteins, mediate the transport of large macromolecules across the outer membrane of Gram-negative bacteria. Limited proteolysis of secretin PulD from the Klebsiella oxytoca pullulanase secretion pathway showed that it consists of an N-terminal domain and a protease-resistant C-terminal domain t...

High resolution AFM topographs of the Escherichia coli water channel aquaporin Z.

Scheuring, S Ringler, P Borgnia, M Stahlberg, H Müller, D J Agre, P Engel, A

Published in The EMBO journal

Aquaporins form a large family of membrane channels involved in osmoregulation. Electron crystallography has shown monomers to consist of six membrane spanning alpha-helices confirming sequence based predictions. Surface exposed loops are the least conserved regions, allowing differentiation of aquaporins. Atomic force microscopy was used to image ...

Opposing activities of IFITM proteins in SARS‐CoV‐2 infection

LRRK 2 regulates endoplasmic reticulum–mitochondrial tethering through the PERK ‐mediated ubiquitination pathway

Optimal sidestepping of intraflagellar transport kinesins regulates structure and function of sensory cilia

α‐Actinin‐1 promotes activity of the L‐type Ca 2+ channel Ca v1.2

Domain structure of secretin PulD revealed by limited proteolysis and electron microscopy.

High resolution AFM topographs of the Escherichia coli water channel aquaporin Z.

The Sir4 H‐ BRCT domain interacts with phospho‐proteins to sequester and repress yeast heterochromatin

Loss of the maintenance methyltransferase, xD nmt1, induces apoptosis in Xenopus embryos

Retraction: Regulation of MBD1-mediated transcriptional repression by SUMO and PIAS proteins.

Phosphatidylinositol 4,5‐bisphosphate controls Rab7 and PLEKHM 1 membrane cycling during autophagosome–lysosome fusion

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