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A thermodynamic switch modulates abscisic acid receptor sensitivity

Published in The EMBO Journal

BAX inhibitor‐1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response

Published in The EMBO Journal

Complete suppression of Htt fibrillization and disaggregation of Htt fibrils by a trimeric chaperone complex

Published in The EMBO Journal

Inactive variants of death receptor p75 NTR reduce Alzheimer’s neuropathology by interfering with APP internalization

Published in The EMBO Journal

A protein palmitoylation cascade regulates microtubule cytoskeleton integrity in Plasmodium

Published in The EMBO Journal

An alternative miRISC targets a cancer-associated coding sequence mutation in FOXL2.

Published in The EMBO journal

SARS‐CoV‐2 sensing by RIG‐I and MDA5 links epithelial infection to macrophage inflammation

Published in The EMBO Journal

SARS‐CoV‐2 infection causes broad‐spectrum immunopathological disease, exacerbated by inflammatory co‐morbidities. A better understanding of mechanisms underpinning virus‐associated inflammation is required to develop effective therapeutics. Here we discover that SARS‐CoV‐2 replicates rapidly in lung epithelial cells despite triggering a robust inn...

Programmable C-to-U RNA editing using the human APOBEC3A deaminase.

Published in The EMBO journal

The UBA domain of conjugating enzyme Ubc1/Ube2K facilitates assembly of K48/K63‐branched ubiquitin chains

Published in The EMBO Journal

Binding of K63‐linked ubiquitin chains via a tightly‐linked accessory domains allows two homologous human and yeast E2 enzymes to add further K48‐linked moieties and build branched conjugates.

Syncytia formation by SARS‐CoV‐2‐infected cells

Published in The EMBO Journal