Silverberg, J I Lai, J-S Patel, K R Singam, V Vakharia, P P Chopra, R Sacotte, R Kantor, R Hsu, D Y Cella, D
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Published in
The British journal of dermatology
Little is known about the validity of numeric rating scales (NRS) and verbal rating scales (VRS) for itch and itch frequency for assessing itch severity in atopic dermatitis (AD). We evaluated the Patient-Reported Outcomes Information System (PROMIS® ) Itch Questionnaire (PIQ) - itch severity assessment, including multiple NRS, VRS and frequency of...
Uter, W Gefeller, O Mahler, V Geier, J
Published in
The British journal of dermatology
Changing patterns of exposure lead to changes in the spectrum of contact allergy in the general population and in patients patch tested for suspected contact allergy. The main contact allergens (haptens) are assembled in the so-called 'baseline series'. To present the current spectrum of contact allergy to baseline series allergens, and its tempora...
Sabroe, R A
Published in
The British journal of dermatology
Engelman, D Yoshizumi, J Hay, R J Osti, M Micali, G Norton, S Walton, S Boralevi, F Bernigaud, C Bowen, A C
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Published in
The British journal of dermatology
Scabies is a common parasitic skin condition that causes considerable morbidity globally. Clinical and epidemiological research for scabies has been limited by a lack of standardization of diagnostic methods. To develop consensus criteria for the diagnosis of common scabies that could be implemented in a variety of settings. Consensus diagnostic cr...
Abji, F Lee, K-A Pollock, R A Machhar, R Cook, R J Chandran, V Gladman, D D
Published in
The British journal of dermatology
We previously found that serum levels of chemokine (C-X-C motif) ligand 10 (CXCL10) decreased after the onset of psoriatic arthritis (PsA). We measured CXCL10 levels over time in patients with psoriasis who developed PsA to determine whether the drop in CXCL10 was specific to these patients and further assess its association with PsA development. P...
Martins, C Darrigade, A-S Jacquemin, C Barnetche, T Taieb, A Ezzedine, K Boniface, K Seneschal, J
Published in
The British journal of dermatology
Vitiligo is a chronic inflammatory skin disorder characterized by the loss of melanocytes. While a T helper cell (Th)1/cytotoxic T cell (Tc)1-skewed immune response is now well demonstrated in vitiligo, recent data suggest that the T-cell component could be more complex, involving different combinatorial T-cell subsets. To analyse the phenotype and...
Adalsteinsson, J A Ratner, D Olafsdóttir, E Grant-Kels, J Ungar, J Silverberg, J I Kristjansson, A K Jonasson, J G Tryggvadottir, L
Published in
The British journal of dermatology
An epidemic of basal cell carcinoma (BCC) has led to a significant healthcare burden in white populations. To provide an update on incidence rates and tumour burden in an unselected, geographically isolated population that is exposed to a low level of ultraviolet radiation. This was a whole-population study using a cancer registry containing record...
Lei, D K Yousaf, M Janmohamed, S R Vakharia, P P Chopra, R Sacotte, R Patel, K R Singam, V Immaneni, S Kantor, R
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Published in
The British journal of dermatology
Sleep disturbances are common in adults with atopic dermatitis (AD). Patient-Reported Outcomes Measurement Information System (PROMIS) Sleep Disturbance (SD) and Sleep-Related Impairment (SRI) are validated questionnaires to assess sleep in adults. Little is known about their measurement properties in adults with AD. To assess the measurement prope...
Yang, C-W Cho, Y-T Hsieh, Y-C Hsu, S-H Chen, K-L Chu, C-Y
Published in
The British journal of dermatology
Drug reaction with eosinophilia and systemic symptoms (DRESS) is a condition caused by a drug-induced immune response. Previous reports have found that CXCL10, also known as interferon-γ-induced protein (IP)-10, may participate in the pathogenesis of cutaneous adverse drug reactions. However, the exact role of IP-10 in DRESS and Stevens-Johnson syn...
Lu, J D Hobbs, M M Huang, W W Ortega-Loayza, A G Alavi, A
Published in
The British journal of dermatology
Pyoderma gangrenosum (PG) is a rare autoinflammatory skin condition that causes tissue destruction and subsequent painful ulcers. To date, there are no core domains or instruments for assessing PG severity in clinical trials, and current treatment paradigms rely on outcome measurements that have not been well characterized in the literature. To per...
