A circadian mechanism for idiopathic hypersomnia - a long biological night.
Published in Sleep medicine
Low risk of iron overload or anaphylaxis during treatment of restless legs syndrome with intravenous iron: a consecutive...
...Published in Sleep medicine
To evaluate the incidence of iron overload and anaphylaxis following intravenous (IV) iron treatment of restless legs syndrome (RLS). A total of 58 consecutive RLS patients, meeting clinical requirements for IV iron treatment according to current IRLSSG guidelines were recruited. IV iron treatment consisted of two 500 mg infusions of ferric carboxy...
Significance of determining plasma orexin levels and analysis of related factors for the diagnosis of patients with narc...
Published in Sleep medicine
Decreased cerebrospinal fluid (CSF) orexin levels are one of the diagnostic and classification criteria for narcolepsy. Because of the difficulty in obtaining CSF, its clinical application is limited. Here, we aimed to confirm the significance of determining plasma orexin levels in the diagnosis and treatment of narcolepsy by comparing the differen...
Variation of circadian activity rhythm according to body mass index in children.
Published in Sleep medicine
This study aimed to examine the variations of circadian activity rhythm of children according to objective body mass index (BMI) values, using a novel statistical framework (ie, Functional Linear Modeling, FLM), separately for school- and weekend days. A total of 107 participants (60 females; mean age: 10.25 ± 0.48 years) wore an actigraph for seve...
The associations of insomnia symptoms and chronotype with daytime sleepiness, mood symptoms and suicide risk in adolesce...
Published in Sleep medicine
To investigate the association of insomnia and chronotype preference with daytime impairment and psychopathology in a community sample of adolescents in Hong Kong. This was a cross-sectional study that included seven local secondary schools in Hong Kong. A total of 1667 adolescents (mean age: 14.8 ± 1.6 years old; boys: 56.5%) returned a battery of...
Female and male sleep duration in association with the probability of conception in two representative populations of re...
Published in Sleep medicine
Sleep duration has been found to affect some reproductive phenotypes but fecundability has been rarely researched. We aim to evaluate the association between female/male sleep duration and the probability of conception in two representative populations. The present study uses two datasets, namely, a cross-sectional dataset of 9137 reproductive-age ...
Evaluation of late atrial enhancement by cardiac magnetic resonance imaging in patients with obstructive sleep apnea.
Published in Sleep medicine
Atrial fibrillation (AF) is a growing public health problem especially due to its association with thromboembolic phenomena. Among its risk factors, obstructive sleep apnea (OSA) has increased in incidence and is often under diagnosed. OSA increases the risk of AF by mechanisms not fully known, but it may lead to remodeling and structural alteratio...
Polygenic score for sleep duration. Association with cognition.
Published in Sleep medicine
Age-related changes in sleep include a reduction in total sleep time and a greater incidence of sleep disorders, and are also an integral part of neurodegenerations. In the present study, we aimed to: a) identify common genetic variants that may influence self-reported sleep duration, and b) examine the association between the identified genetic va...
Association of napping and all-cause mortality and incident cardiovascular diseases: a dose-response meta analysis of co...
Published in Sleep medicine
Napping is a habit prevalent worldwide and occurs from an early age. However, the association between napping and the risk of incident cardiovascular disease (CVD) and all-cause mortality remains unclear. We conducted a systematic search of Medline, Embase, and Cochrane databases from inception to December 2019 for cohort studies investigating the ...
Encephalitis lethargica epidemic milestones in early sleep neurobiology researches.
Published in Sleep medicine
Around 100 years ago, the outbreak of peculiar encephalitis promoted knowledge advancement regarding sleep and psychomotricity control. This epidemic is believed to have disappeared ten years after it started, and it remained from 1916 to 1927. Since then, only a few sporadic cases have been reported, but previously, they happened in occasional and...
