Epiregulin: Roles in normal physiology and cancer
Published in Seminars in Cell and Developmental Biology
Published in Seminars in Cell and Developmental Biology
Published in Seminars in Cell and Developmental Biology
Published in Seminars in Cell and Developmental Biology
Published in Seminars in Cell and Developmental Biology
Published in Seminars in Cell and Developmental Biology
Published in Seminars in Cell and Developmental Biology
Published in Seminars in Cell and Developmental Biology
Published in Seminars in Cell and Developmental Biology
Published in Seminars in cell & developmental biology
This review summarizes our current understanding of exocrine pancreas development, including the formation of acinar, ductal and centroacinar cells. We discuss the transcription factors associated with various stages of exocrine differentiation, from multipotent progenitor cells to fully differentiated acinar and ductal cells. Within the branching ...
Published in Seminars in cell & developmental biology
Global folding of polypeptides entering the endoplasmic reticulum (ER) starts as soon as they emerge from the narrow Sec61 translocon. Attainment of the native structure can take from several minutes to hours, depending on the gene product. Until then, non-native folding intermediates must be protected from molecular chaperones that recognize misfo...