Filipiak, Michał Woyciechowski, Michal Czarnoleski, Marcin
Published in
Scientific Reports
Life histories of species may be shaped by nutritional limitations posed on populations. Yet, populations contain individuals that differ according to sex and life stage, each of which having different nutritional demands and experiencing specific limitations. We studied patterns of resource assimilation, allocation and excretion during the growth ...
Malaisé, Yann Lencina, Corinne Cartier, Christel Olier, Maïwenn Ménard, Sandrine Guzylack-Piriou, Laurence
Published in
Scientific Reports
Bisphenol (BP)A is an endocrine disruptor (ED) widely used in thermal papers. Regulatory restrictions have been established to prevent risks for human health, leading to BPA substitution by structural analogues, like BPS and BPF. We previously demonstrated that oral perinatal exposure to BPA had long-term consequences on immune responses later in l...
Abbasi, Bilal Haider Khan, Taimoor Khurshid, Razia Nadeem, Muhammad Drouet, Samantha Hano, Christophe
Published in
Scientific Reports
Fagonia indica (L.) is an important medicinal plant with multitude of therapeutic potentials. Such application has been attributed to the presence of various pharmacological important phytochemicals. However, the inadequate biosynthesis of such metabolites in intact plants has hampered scalable production. Thus, herein, we have established an in vi...
Tapia-Guerra, Jan M. Mecho, Ariadna Easton, Erin E. Gallardo, María de los Ángeles Gorny, Matthias Sellanes, Javier
Published in
Scientific Reports
Seamounts and oceanic islands of the Chilean Exclusive Economic Zone at the intersection of the Nazca and Salas y Gómez ridges lie within one of the least explored areas in the world. The sparse information available, mainly for seamounts outside Chilean jurisdiction and shallow-water fauna of the Desventuradas Islands, suggests that the area is a ...
Noguchi, Hiroshi Pierre-Louis, Olivier
Published in
Scientific Reports
Biomembranes experience out-of-equilibrium conditions in living cells. Their undulation spectra are different from those in thermal equilibrium. Here, we report on the undulation of a fluid membrane pushed by the stepwise growth of filaments as in the leading edge of migrating cells, using three-dimensional Monte Carlo simulations. The undulations ...
Bonnard, Benjamin Martínez-Martínez, Ernesto Fernández-Celis, Amaya Pieronne-Deperrois, Marie Do, Quoc-Tuan Ramos, Isbaal Rossignol, Patrick Zannad, Faiez Mulder, Paul Ouvrard-Pascaud, Antoine
...
Published in
Scientific Reports
Neutrophil gelatinase-associated lipocalin (NGAL) is involved in cardiovascular and renal diseases. Gene inactivation of NGAL blunts the pathophysiological consequences of cardiovascular and renal damage. We aimed to design chemical NGAL inhibitors and investigate its effects in experimental models of myocardial infarction (MI) and chronic kidney d...
Di Giuseppe, Dario Perchiazzi, Natale Brunelli, Daniele Giovanardi, Tommaso Nodari, Luca Della Ventura, Giancarlo Malferrari, Daniele Maia, Marcia Gualtieri, Alessandro F.
Published in
Scientific Reports
Tremolite is one of the most common amphibole species and, in the fibrous form (i.e., characterized by crystals/particles consisting of fibres with length > 5 µm, width 3), one of the six asbestos minerals. Until now the attention of crystallographers has focused only on samples from continental environment. Here we report the first chemical and s...
Liu, JingJing Madec, Jean-Yves Bousquet-Mélou, Alain Haenni, Marisa Ferran, Aude A.
Published in
Scientific Reports
In S. aureus biofilms, bacteria are embedded in a matrix of extracellular polymeric substances (EPS) and are highly tolerant to antimicrobial drugs. We thus sought to identify non-antibiotic substances with broad-spectrum activity able to destroy the EPS matrix and enhance the effect of antibiotics on embedded biofilm bacteria. Among eight substanc...
Morisse, Pierre Marchet, Camille Limasset, Antoine Lecroq, Thierry Lefebvre, Arnaud
Published in
Scientific Reports
Third-generation sequencing technologies allow to sequence long reads of tens of kbp, that are expected to solve various problems. However, they display high error rates, currently capped around 10%. Self-correction is thus regularly used in long reads analysis projects. We introduce CONSENT, a new self-correction method that relies both on multipl...
Sell, Gabrielle L Xin, Wendy Cook, Emily K Zbinden, Mark A Schaffer, Thomas B O'Meally, Robert N Cole, Robert N Margolis, Seth S
Published in
Scientific reports
In humans, loss-of-function mutations in the UBE3A gene lead to the neurodevelopmental disorder Angelman syndrome (AS). AS patients have severe impairments in speech, learning and memory, and motor coordination, for which there is currently no treatment. In addition, UBE3A is duplicated in > 1-2% of patients with autism spectrum disorders-a further...
