Mukadam, Aamir S Miller, Lauren VC Smith, Annabel E Vaysburd, Marina Sakya, Siri A Sanford, Sophie Keeling, Sophie Tuck, Benjamin J Katsinelos, Taxiarchis Green, Chris
...
Published in
Science (New York, N.Y.)
Aggregates of the protein tau are proposed to drive pathogenesis in neurodegenerative diseases. Tau can be targeted using passively transferred antibodies (Abs) but the mechanisms of Ab protection are incompletely understood. Here we used a variety of cell and animal model systems and showed that the cytosolic Ab receptor and E3 ligase TRIM21 (T21)...
Saeedi, Kamyar Simmons, Stephanie Salvail, Jeff Z Dluhy, Phillip Riemann, Helge Abrosimov, Nikolai V Becker, Peter Pohl, Hans-Joachim Morton, John J L Thewalt, Mike L W
...
Published in
Science (New York, N.Y.)
Quantum memories capable of storing and retrieving coherent information for extended times at room temperature would enable a host of new technologies. Electron and nuclear spin qubits using shallow neutral donors in semiconductors have been studied extensively but are limited to low temperatures (≲10 kelvin); however, the nuclear spins of ionized ...
Voosen, Paul
Published in
Science (New York, N.Y.)
Eruption spotted in 30-year-old data from Magellan mission.
Kupferschmidt, Kai
Published in
Science (New York, N.Y.)
London meeting touts sickle cell success, but questions about embryo editing linger.
Giannakis, Marios Ng, Kimmie
Published in
Science (New York, N.Y.)
The etiology of early-onset colorectal cancer needs to be understood to tackle rising incidence.
Plewnia, Amadeus Böning, Philipp Lötters, Stefan
Published in
Science (New York, N.Y.)
Vogel, Gretchen
Published in
Science (New York, N.Y.)
Ineffective or outdated requirements could undermine trust, some vaccine researchers say.
Loeffler-Henry, Karl Kang, Changku Sherratt, Thomas N
Published in
Science (New York, N.Y.)
The initial evolution of warning signals in unprofitable prey, termed aposematism, is often seen as a paradox because any new conspicuous mutant would be easier to detect than its cryptic conspecifics and not readily recognized by naïve predators as defended. One possibility is that permanent aposematism first evolved through species using hidden w...
Service, Robert F
Published in
Science (New York, N.Y.)
Corrosion-proof electrolyzers could tap ample supplies of saltwater.
Mervis, Jeffrey
Published in
Science (New York, N.Y.)
But Congress will have its own views on setting funding levels for research agencies.