Castillo-Higuera, Tatiana Alarcón-Granados, María Camila Marin-Suarez, Johana Moreno-Ortiz, Harold Esteban-Pérez, Clara Inés Ferrebuz-Cardozo, Atilio Junior Forero-Castro, Maribel Camargo-Vill Alba, Gloria
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Reproductive sciences (Thousand Oaks, Calif.)
Polycystic ovary syndrome (PCOS) is one of the most common endocrine-metabolic disorders in women of reproductive age. It is characterized by an increase in the biosynthesis of androgens, anovulation, and infertility. PCOS has been reported as a polygenic entity in which multiple single nucleotide polymorphisms (SNPs) are associated with the clinic...
Jahmani, M Y Hammadeh, M E Al Smadi, M A Baller, Marko K
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Reproductive sciences (Thousand Oaks, Calif.)
Chromatin condensation is one of the main factors essential for sperm function. Evaluation of chromatin condensation by current methods render the assessed sperm unsuitable for assisted reproduction. We examined the Raman spectra of normal morphology sperm to determine whether a non-invasive confocal Raman spectroscopy can detect spectral differenc...
Thankachan, Sanu Bhardwaj, Boddapati Kalyani Venkatesh, Thejaswini Suresh, Padmanaban S
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Reproductive sciences (Thousand Oaks, Calif.)
Long non-coding RNAs (lncRNAs) are emerging regulators of cellular pathways, especially in cancer development. Among the lncRNAs, nuclear paraspeckle assembly transcript 1 (NEAT1) forms a scaffold for a nuclear body; the paraspeckle and aberrant expression of NEAT1 have been reported in breast and gynecologic cancers (ovarian, cervical, endometrial...
Huang, Runzhi Sun, Hanlin Yan, Gaili Zhang, Lili Sun, Wenhuizi Zhang, Jie Yin, Huabin Xian, Shuyuan Hu, Peng Yan, Penghui
...
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Reproductive sciences (Thousand Oaks, Calif.)
Uterine carcinosarcoma (UCS) is a malignant tumor with a high tendency to invasion and metastasis. However, the underlying invasion and metastasis mechanisms of UCS remain poorly understood. Genetic alteration and tumor-infiltrating immune cells play important roles in tumorigenesis, progression, and metastasis. To better understand the underlying ...
Ngadjui, Esther Kouam, Jibril Yves Fozin, Georges Romeo Bonsou Momo, Aimé Césaire Tetsatsi Deeh, Patrick Brice Defo Wankeu-Nya, Modeste Nguelefack, Telesphore Benoit Watcho, Pierre
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Reproductive sciences (Thousand Oaks, Calif.)
Lannea acida (Anacardiaceae), commonly called Kikié in the Noun division (West-Cameroon), is a tree whose bark is used locally to facilitate delivery. This study was aimed at evaluating the in vitro uterotonic effects of aqueous and methanol extracts of L. acida in Wistar rats. Uterine strips isolated from rats pretreated with 5 μg estradiol (48 h)...
Taşkıran, Gizem Özgül, Serap
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Reproductive sciences (Thousand Oaks, Calif.)
This study aims to analyze the relationship/effect of a wide range of individual factors with/on menopausal symptom severity (MSS) and menopause-specific quality of life (MSQoL) in rural Turkish women. This cross-sectional study included rural perimenopausal/postmenopausal women. Demographic (age, marital status, and education and employment status...
Akdaş Reis, Yıldız Tapisiz, Omer Lutfi Göktolga, Ümit Şimşek, Gülçin Erten, Özlem Kiykaç Altinbaş, Şadıman Erkaya, Salim
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Reproductive sciences (Thousand Oaks, Calif.)
Postoperative adhesions can cause serious complications, including intestinal obstruction, chronic abdominopelvic pain, and infertility in women. Here we investigate the effects of disulfiram on the postoperative adhesion model. Female Wistar rats were used (n = 72). The animals were separated into six groups (12 rats per group): group 1 (control),...
Yang, Seung Chel Yu, Eun Jeong Park, Jae Kyun Kim, Tae Hyung Eum, Jin Hee Paek, Soo Kyung Hwang, Ji Young Lyu, Sang Woo Kim, Jin Young Lee, Woo Sik
...
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Reproductive sciences (Thousand Oaks, Calif.)
Previous studies have reported that the mitochondrial DNA (mtDNA) contents of cumulus cells (CCs) in ovarian follicular fluid are correlated with embryo quality. Quantification of mtDNA CCs has been suggested as a biomarker of embryo viability. The aim of this study was to determine the relationship between mitochondrial DNA (mtDNA)/genomic DNA (gD...
Wang, Xiuwei Yue, Huixuan Li, Shen Guo, Jin Guan, Zhen Zhu, Zhiqiang Niu, Bo Zhang, Ting Wang, Jianhua
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Reproductive sciences (Thousand Oaks, Calif.)
Apurinic/apyrimidinic endonuclease 1/redox-factor 1 (APE1/Ref-1) gene encodes a multifunctional protein involved in the DNA base excision repair (BER) pathway, which initiates repair of apurinic/apyrimidinic (AP) sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone. APE1/Ref-1 polymorphisms are related to the occurrence of ...
Ware, Courtney A Buhimschi, Catalin S Zhao, Guomao El Helou, Yara Buhimschi, Irina A
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Reproductive sciences (Thousand Oaks, Calif.)
Preterm birth is an important determinant of neonatal morbidity and mortality and intra-amniotic infection (IAI) and inflammation play a causative role. The constitutive proteasome and immunoproteasome are key players in maintenance of proteostasis and their alteration outside pregnancy has been linked to pathogenesis of numerous inflammatory disea...
