Naftolin, Frederick Garcia-Segura, Luis Miguel Horvath, Tamas L Zsarnovszky, Attila Demir, Necdet Fadiel, Ahmed Leranth, Csaba Vondracek-Klepper, Susanne Lewis, Carole Chang, Aimee
...
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Reproductive sciences (Thousand Oaks, Calif.)
Proper gonadal function requires coordinated (feedback) interactions between the gonads, adenohypophysis, and brain: the gonads elaborate sex steroids (progestins, androgens, and estrogens) and proteins (inhibin-activin family) during gamete development. In both sexes, the brain-pituitary gonadotrophin-regulating interaction is coordinated by estra...
Chan, Te-Fu Chen, Hung-Sheng Chen, Yu-Chieh Lee, Chien-Hung Chou, Fan-Hao Chen, I-Ju Chen, Su-Yin Jong, Shiang-Bin Tsai, Eing-Mei
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Reproductive sciences (Thousand Oaks, Calif.)
The authors hypothesized that serum retinol-binding protein 4 (RBP4) concentrations will be higher in gestational diabetes mellitus (GDM) subjects. This study tested both women with GDM and healthy pregnant women and correlated their serum RBP4 concentrations with body mass index (BMI) and a variety of other parameters. Also, since there is no info...
Güney, Mehmet Nasir, Serdar Oral, Baha Karahan, Nermin Mungan, Tamer
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Reproductive sciences (Thousand Oaks, Calif.)
The objective of this study is to determine the effects of antioxidant and anti-inflammatory caffeic acid phenethyl ester (CAPE) on experimental endometriosis, peritoneal superoxide dismutase (SOD) and catalase (CAT) activities, and malondialdehyde (MDA) levels in the rat endometriosis model. Thirty rats with experimentally induced endometriosis we...
Meyer, Kurt
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Reproductive sciences (Thousand Oaks, Calif.)
Fetal programming describes long-term adaptive changes that an organism undergoes in response to an intrauterine insult. This term was coined to describe the increased incidence of adult disease, such as cardiovascular disease, seen among populations that suffered an intrauterine insult. While changes induced by such an insult may be initially bene...
Madsen, Gemma Macintyre, David A Mesiano, Sam Smith, Roger
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Reproductive sciences (Thousand Oaks, Calif.)
Immunoblotting is used to characterize the various nuclear progesterone receptor (nPR) isoforms present in tissues; however, the success of this technique is dependent on the specificity of the primary nPR antibody. The authors investigate the specificity of a frequently used nPR antibody, sc-538, in total protein from human myometrium and a myomet...
Torricelli, Michela Giovannelli, Alessia Leucci, Eleonora De Falco, Giulia Reis, Fernando M Imperatore, Alberto Florio, Pasquale Petraglia, Felice
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Reproductive sciences (Thousand Oaks, Calif.)
Because maternal plasma corticotrophin-releasing factor (CRF) levels increase during the last weeks of pregnancy and at parturition, the present study evaluated whether placental mRNA expression of CRF and CRF-binding protein (CRF-BP) are modified in preterm delivery. A group of 30 women with singleton pregnancies were enrolled in the study. A plac...
Gheorghe, Ciprian P Mohan, Subburaman Oberg, Kerby C Longo, Lawrence D
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Reproductive sciences (Thousand Oaks, Calif.)
Hypoxia has been identified as a major stress or in placental and fetal development. To test the hypothesis that hypoxic stress responses are associated with gene expression changes, the authors measured gene expression in the mouse placenta in response to 48 hours of hypoxia. Embryonic day 15.5 pregnant mice were exposed to 48 hours of hypoxia (10...
Dayioglu, Emel Buharalioglu, C Kemal Saracoglu, Ferit Akar, Fatma
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Reproductive sciences (Thousand Oaks, Calif.)
The authors investigate the effect of bumetan ide, an inhibitor of NKCC1 and a loop diuretic, on the tone of human umbilical artery (HUA). Rings of HUA (n = 35) from vaginal deliveries were suspended for isometric tension recordings in organ baths. Cumulative concentration-response curves to serotonin, histamine, and KCl were performed in the absen...
Darwish, Atef M Farah, Emad Gadallah, Wafaa A Mohammad, Ibraheem I
Published in
Reproductive sciences (Thousand Oaks, Calif.)
The objective of this study is to verify the safety and efficacy of new vaginal bioadhesive suppositories as compared with vaginal use of commercial bromocriptine tablets in hyperprolactinemic patients. This study is a randomized, double-blind, active comparator clinical trial in which a subset of patients had some pharmacokinetic measurements. The...
Amidi, Fataneh Beall, Marie Ross, Michael G
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Reproductive sciences (Thousand Oaks, Calif.)
Cell membrane aquaporins (AQPs) may con t r i b u t e importantly to the regulation of intramembranous absorption of amniotic fluid. Recently, the authors demonstrated that human amnion AQP3 expression is upregulated by second-messenger cyclic adenosine monophosphate (cAMP). The present study was undertaken to determine the cAMP regulation of other...
