Asgedom, Solomon Weldegebreal Amanuel, Kidus Gidey, Meles Tekie Niriayo, Yirga Legesse Gidey, Kidu Atey, Tesfay Mehari
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PloS one
Treatment resistant hypertension(TRH) is detrimental risk of cardiovascular and premature deaths. Globally, the prevalence of resistant hypertension is inclining from time to time and it is yet to be determined in Ethiopia. To assess the prevalence of apparent TRH and its predictors among ambulatory hypertensive patients on follow up in hypertensio...
Leu, Costin Richardson, Tom G Kaufmann, Tobias van der Meer, Dennis Andreassen, Ole A Westlye, Lars T Busch, Robyn M Davey Smith, George Lal, Dennis
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PloS one
Epilepsy is clinically heterogeneous, and neurological or psychiatric comorbidities are frequently observed in patients. It has not been tested whether common risk variants for generalized or focal epilepsy are enriched in people with other disorders or traits related to brain or cognitive function. Here, we perform two brain-focused phenome associ...
O'Connor, Aisling Máire Cousins, Gráinne Durand, Louise Barry, Joe Boland, Fiona
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PloS one
Retention in opioid substitution (OST) treatment is associated with substantial reductions in all cause and overdose mortality. This systematic review aims to identify both protective factors supporting retention in OST, and risk factors for treatment dropout. A systematic search was performed using MEDLINE, Embase, PsycInfo, CINAHL and Web of Scie...
Ko, Yu-Chieh Wey, Shih-Yu Chen, Wei-Ta Chang, Yu-Fan Chen, Mei-Ju Chiou, Shih-Hwa Liu, Catherine Jui-Ling Lee, Chen-Yi
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PloS one
To evaluate ways to improve the generalizability of a deep learning algorithm for identifying glaucomatous optic neuropathy (GON) using a limited number of fundus photographs, as well as the key features being used for classification. A total of 944 fundus images from Taipei Veterans General Hospital (TVGH) were retrospectively collected. Clinical ...
Moglia, Andrea Florio, Francesco Elia Iacopino, Sergio Guerrieri, Alessandra Milani, Anna Maria Comino, Cinzia Barchi, Larenzo Marengo, Arianna Cagliero, Cecilia Rubiolo, Patrizia
...
Published in
PloS one
Here we focus on the highly conserved MYB-bHLH-WD repeat (MBW) transcriptional complex model in eggplant, which is pivotal in the transcriptional regulation of the anthocyanin biosynthetic pathway. Through a genome-wide approach performed on the recently released Eggplant Genome (cv. 67/3) previously identified, and reconfirmed by us, members belon...
Ray, Krishnendu Sen, Piyali Goswami, Rupak Sarkar, Sukamal Brahmachari, Koushik Ghosh, Argha Nanda, Manoj Kumar Mainuddin, Mohammed
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PloS one
This study compares thirteen rice-based cropping systems in the coastal part of West Bengal, India in terms of productivity, profitability, energetics, and emissions. Information on the crop management practices of these systems was collected on 60 farms through a questionnaire survey. Rice-bitter gourd system was observed to have the highest syste...
Silva, Isabelle Leticia Zaboroski Robert, Anny Waloski Cabo, Guillermo Cabrera Spangenberg, Lucia Stimamiglio, Marco Augusto Dallagiovanna, Bruno Gradia, Daniela Fiori Shigunov, Patrícia
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PloS one
Posttranscriptional regulation plays a fundamental role in the biology of embryonic stem cells (ESCs). Many studies have demonstrated that multiple mRNAs are coregulated by one or more RNA-binding proteins (RBPs) that orchestrate mRNA expression. A family of RBPs, which is known as the Pumilio-FBF (PUF) family, is highly conserved among different s...
Chamie, Gabriel Ndyabakira, Alex Marson, Kara G Emperador, Devy M Kamya, Moses R Havlir, Diane V Kwarisiima, Dalsone Thirumurthy, Harsha
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PloS one
Retesting for HIV is critical to identifying newly-infected persons and reinforcing prevention efforts among at-risk adults. Incentives can increase one-time HIV testing, but their role in promoting retesting is unknown. We sought to test feasibility and acceptability of incentive strategies, including commitment contracts, to promote HIV retesting...
Hemida, Manal Vuori, Kristiina A Salin, Siru Moore, Robin Anturaniemi, Johanna Hielm-Björkman, Anna
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PloS one
A cross-sectional hypothesis generating study was performed to investigate modifiable exposures such as whether feeding pattern (a non-processed meat based diet, NPMD, or an ultra-processed carbohydrate based diet, UPCD), certain environmental factors and their timing of exposure might be associated with the development of canine atopic dermatitis ...
Mola, Saraï Foisy, Sylvain Boucher, Gabrielle Major, François Beauchamp, Claudine Karaky, Mohamad Goyette, Philippe Lesage, Sylvie Rioux, John D
Published in
PloS one
Genome-wide transcriptomic analyses have provided valuable insight into fundamental biology and disease pathophysiology. Many studies have taken advantage of the correlation in the expression patterns of the transcriptome to infer a potential biologic function of uncharacterized genes, and multiple groups have examined the relationship between co-e...