Petrova, Dafina Špacírová, Zuzana Fernández-Martínez, Nicolás Francisco Ching-López, Ana Garrido, Dunia Rodríguez-Barranco, Miguel Pollán, Marina Redondo-Sánchez, Daniel Espina, Carolina Higueras-Callejón, Camila
...
Published in
PLoS Medicine
Why was this study done? Cancer is a leading cause of death globally and timely diagnosis and treatment are considered essential for improving cancer outcomes. Three main intervals describe the time patients spend in the pathway to treatment of cancer: the patient interval (from symptom start to first presentation to a healthcare professional), the...
Sabia, Séverine Dugravot, Aline Léger, Damien Ben Hassen, Céline Kivimaki, Mika Singh-Manoux, Archana
Published in
PLoS medicine
Sleep duration has been shown to be associated with individual chronic diseases but its association with multimorbidity, common in older adults, remains poorly understood. We examined whether sleep duration is associated with incidence of a first chronic disease, subsequent multimorbidity and mortality using data spanning 25 years. Data were drawn ...
Adanikin, Abiodun Lawlor, Deborah A Pell, Jill P Nelson, Scott M Smith, Gordon C S Iliodromiti, Stamatina
Published in
PLoS medicine
Birthweight centiles beyond the traditional thresholds for small or large babies are associated with adverse perinatal outcomes but there is a paucity of data about the relationship between birthweight centiles and childhood development among children born from 37 weeks of gestation. This study aims to establish the association between birthweight ...
Bandy, Lauren K Hollowell, Sven Jebb, Susan A Scarborough, Peter
Published in
PLoS medicine
Excess consumption of salt is linked to an increased risk of hypertension and cardiovascular disease. The United Kingdom has had a comprehensive salt reduction programme since 2003, setting a series of progressively lower, product-specific reformulation targets for the food industry, combined with advice to consumers to reduce salt. The aim of this...
Aggarwal, Rahul Yeh, Robert W Dahabreh, Issa J Robertson, Sarah E Wadhera, Rishi K
Published in
PLoS medicine
US policymakers are debating whether to expand the Medicare program by lowering the age of eligibility. The goal of this study was to determine the association of Medicare eligibility and enrollment with healthcare access, affordability, and financial strain from medical bills in a contemporary population of low- and higher-income adults in the US....
Si, Keyi Hu, Yang Wang, Molin Apovian, Caroline M Chavarro, Jorge E Sun, Qi
Published in
PLoS medicine
Weight loss is crucial for disease prevention among individuals with overweight or obesity. This study aimed to examine associations of weight loss strategies (WLSs) with weight change and type 2 diabetes (T2D) risk among US health professionals. This study included 93,110 participants (24 to 60 years old; 11.6% male) from the Nurses' Health Study ...
Godfrey-Faussett, Peter Frescura, Luisa Abdool-Karim, Quarraisha Clayton, Michaela Ghys, Peter D
Published in
PLoS medicine
UNAIDS and a broad range of partners have collaborated to establish a new set of HIV prevention targets to be achieved by 2025 as an intermediate step towards the sustainable development target for 2030.The number of new HIV infections in the world continues to decline, in part due to the extraordinary expansion of effective HIV treatment. However,...
Zahroh, Rana Islamiah Hazfiarini, Alya Eddy, Katherine E Vogel, Joshua P Tunçalp, Ӧzge Minckas, Nicole Althabe, Fernando Oladapo, Olufemi T Bohren, Meghan A
Published in
PLoS medicine
[This corrects the article DOI: 10.1371/journal.pmed.1004074.].
Wei, Yu-Jung Jenny Chen, Cheng Cheng, Ting-Yuan David Schmidt, Siegfried O Fillingim, Roger B Winterstein, Almut G
Published in
PLoS medicine
Injury, prevalent and potentially associated with prescription opioid use among older adults, has been implicated as a warning sign of serious opioid-related adverse events (ORAEs) including opioid misuse, dependence, and poisoning, but this association has not been empirically tested. The study aims to examine the association between incident inju...
Aarestrup, Julie Blond, Kim Vistisen, Dorte Jørgensen, Marit E. Frimodt-Møller, Marie Jensen, Britt W. Baker, Jennifer L.
Published in
PLoS Medicine
Why was this study done? Worldwide, chronic kidney disease (CKD) is common and associated with numerous adverse health effects. Severe obesity in childhood is associated with impaired kidney health. Little is known on the impact of childhood body size on subsequent development of CKD. What did the researchers do and find? Using a large Danish popul...
