High-coverage plasma lipidomics reveals novel sex-specific lipidomic fingerprints of age and BMI: Evidence from two larg...
...Published in PLoS Biology
Planthopper bugs use a fast, cyclic elastic recoil mechanism for effective vibrational communication at small body size
Published in PLoS Biology
Transmembrane tumor necrosis factor alpha attenuates pressure-overload cardiac hypertrophy via tumor necrosis factor rec...
Published in PLoS Biology
The Yin and Yang of TNF-α signaling in heart failure: this Primer explores the history of failure of TNF-α antagonistic therapy in heart failure and how a recent study suggests that inhibition of TNF-α converting enzyme TACE might be a way out of this dilemma.
We need to keep a reproducible trace of facts, predictions, and hypotheses from gene to function in the era of big data
Published in PLoS Biology
How do we scale biological science to the demand of next generation biology and medicine to keep track of the facts, predictions, and hypotheses? These days, enormous amounts of DNA sequence and other omics data are generated. Since these data contain the blueprint for life, it is imperative that we interpret it accurately. The abundance of DNA is ...
Epidemics on the move: Climate change and infectious disease.
Published in PLoS biology
Find and fuse: Unsolved mysteries in sperm-egg recognition.
Published in PLoS biology
Sexual reproduction is such a successful way of creating progeny with subtle genetic variations that the vast majority of eukaryotic species use it. In mammals, it involves the formation of highly specialised cells: the sperm in males and the egg in females, each carrying the genetic inheritance of an individual. The interaction of sperm and egg cu...
Superspreading events in the transmission dynamics of SARS-CoV-2: Opportunities for interventions and control
Published in PLoS Biology
This Essay discusses how the transmission of COVID-19 is dominated by superspreading events, proposing that finding ways to cut the long tail of secondary infections is important for controlling onward transmission.
Monitor for COVID-19 vaccine resistance evolution during clinical trials.
Published in PLoS biology
Although less common than the evolution of antimicrobial drug resistance, vaccine resistance can and has evolved. How likely is it that COVID-19 vaccines currently in development will be undermined by viral evolution? We argue that this can be determined by repurposing samples that are already being collected as part of clinical trials. Such inform...
Common ground: The foundation of interdisciplinary research on bat disease emergence.
Published in PLoS biology
Human perturbation of natural systems is accelerating the emergence of infectious diseases, mandating integration of disease and ecological research. Bats have been associated with recent zoonoses, but our bibliometric analysis of coauthor relationships identified a separation of bat ecologists and infectious disease researchers with few cross-disc...
Expanding conservation culturomics and iEcology from terrestrial to aquatic realms
...Published in PLoS Biology
The ongoing digital revolution in the age of big data is opening new research opportunities. Culturomics and iEcology, two emerging research areas based on the analysis of online data resources, can provide novel scientific insights and inform conservation and management efforts. To date, culturomics and iEcology have been applied primarily in the ...
