V(D)J recombination and the evolution of the adaptive immune system.
Published in PLoS biology
A functional analysis of the spacer of V(D)J recombination signal sequences.
Published in PLoS biology
During lymphocyte development, V(D)J recombination assembles antigen receptor genes from component V, D, and J gene segments. These gene segments are flanked by a recombination signal sequence (RSS), which serves as the binding site for the recombination machinery. The murine Jbeta2.6 gene segment is a recombinationally inactive pseudogene, but exa...
Digital evolution.
Published in PLoS biology
Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions.
Published in PLoS biology
RNA-mediated interference (RNAi) is a method to inhibit gene function by introduction of double-stranded RNA (dsRNA). Recently, an RNAi library was constructed that consists of bacterial clones expressing dsRNA, corresponding to nearly 90% of the 19,427 predicted genes of C. elegans. Feeding of this RNAi library to the standard wild-type laboratory...
Genetically modified corn--environmental benefits and risks.
Published in PLoS biology
Why PLoS became a publisher.
Published in PLoS biology
Heterochromatin dynamics.
Published in PLoS biology
Out of the way: how the next copyright revolution can help the next scientific revolution.
Published in PLoS biology
Neuroscience networks: data-sharing in an information age.
Published in PLoS biology
PLoS Biology —We're Open
Published in PLoS Biology
With this first issue of PLoS Biology, the editors present the aims and scope of the journal
