Published in PLoS Biology
Assessment of researchers still rarely includes considerations related to trustworthiness, rigor, and transparency. This Essay presents the Hong Kong Principles (HKPs), developed as part of the 6th World Conference on Research Integrity, with a specific focus on the need to drive research improvement by ensuring that researchers are explicitly reco...
Published in PLoS Biology
Currently there are no rules on compiling lists of accepted names of species, meaning that many people use a variety of competing lists, which results in confusion and inefficiencies. This Perspective article provides principles for developing global lists of species that are needed if such lists are to be accepted by both taxonomists and users of ...
Published in PLoS Biology
This Primer explores the implications of a study that describes the first murine model of familial human prion disease, demonstrating the emergence and propagation of two PrP amyloid conformers; of these, one causes neurodegeneration while the other does not. With its many conformers, PrP is a truly protean protein.
Published in PLoS biology
Helping a friend move house, donating to charity, volunteering assistance during a crisis. Humans and other species alike regularly undertake prosocial behaviors-actions that benefit others without necessarily helping ourselves. But how does the brain learn what acts are prosocial? Basile and colleagues show that removal of the anterior cingulate c...
Published in PLoS biology
A key feature of most social relationships is that we like seeing good things happen to others. Research has implicated the anterior cingulate cortex (ACC) in attaching value to social outcomes. For example, single neurons in macaque ACC selectively code reward delivery to the self, a partner, both monkeys, or neither monkey. Here, we assessed whet...
Published in PLoS Biology
This Primer explores how autophagy induction is regulated by the phosphorylation of ATG proteins, and highlights a recent study which reports that phosphorylation of ATG proteins by the cyclin-dependent kinase CDK1 drives cell cycle progression.
Published in PLoS Biology
The genetic adaptation of humans to the consumption of animal milk is a textbook example of gene-culture coevolution. Taking advantage of the accumulated ancient DNA data, this Unsolved Mystery article explores where and when lactase persistence emerged. The mutation rapidly spread throughout Eurasia between 4000 and 3000 BP, but if Asian herders m...
Published in PLoS Biology
Your published research is already being processed with automated tools, and text mining will become more common; this Community Page article describes how you can help these tools process your work more accurately, including a web tool, PubReCheck.
Published in PLoS Biology
Published in PLoS Biology
