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Riddled with holes: Understanding air space formation in plant leaves

Published in PLoS Biology

Leaves are interwoven with large air spaces to increase the efficiency of photosynthesis; however, how these air spaces form and how different patterns have evolved is almost unknown. This Unsolved Mystery article discusses the existing evidence and poses new avenues of research to answer this question.

Homeostatic scaling is driven by a translation-dependent degradation axis that recruits miRISC remodeling

Published in PLoS Biology

This Primer explores the implications of a new study in PLOS Biology which reveals how homeostatic synaptic plasticity requires coordinated and inter-dependent protein synthesis and degradation, as well as remodeling of the miRNA-induced silencing complex.

Advanced human mucosal tissue models are needed to improve preclinical testing of vaccines

Published in PLoS Biology

There is a need for better models to improve preclinical testing of vaccines. This Perspective article argues that advanced mucosal human tissue models could present a solution to this pressing problem in the future.

Extracellular phosphorylation of a receptor tyrosine kinase controls synaptic localization of NMDA receptors and regulat...

Published in PLoS Biology

Correction: Stimulation of the left dorsolateral prefrontal cortex with slow rTMS enhances verbal memory formation.

Published in PLoS biology

[This corrects the article DOI: 10.1371/journal.pbio.3001363.].

iSDAsoil: The first continent-scale soil property map at 30 m resolution provides a soil information revolution for Afri...

Published in PLoS Biology

Recent developments in remote sensing and machine learning have allowed African soil properties to be mapped at an unprecedented resolution of 30 m. iSDAsoil is an open access resource that will empower the community to embrace ’hyperlocal’ approaches such as field-level agronomy advice for smallholder farmers.

The microbiome impacts host hybridization and speciation.

Published in PLoS biology

Microbial symbiosis and speciation profoundly shape the composition of life's biodiversity. Despite the enormous contributions of these two fields to the foundations of modern biology, there is a vast and exciting frontier ahead for research, literature, and conferences to address the neglected prospects of merging their study. Here, we survey and ...

AI delivers Michaelis constants as fuel for genome-scale metabolic models.

Published in PLoS biology

Michaelis constants (Km) are essential to predict the catalytic rate of enzymes, but are not widely available. A new study in PLOS Biology uses artificial intelligence (AI) to accurately predict Km on a proteome-wide scale, paving the way for dynamic, genome-wide modeling of metabolism.

Dilp-2–mediated PI3-kinase activation coordinates reactivation of quiescent neuroblasts with growth of their glial stem ...

Published in PLoS Biology

Social Opportunity Produces Brain Changes in Fish

Published in PLoS Biology