Comment on Corbett et al. entitled “Acupuncture and other physical treatments for the relief of pain due to osteoarthrit...
Published in Osteoarthritis and Cartilage
Both miRNA-29b downregulation and miRNA-140 overexpression drive respectively MSC proliferation and chondrogenic differe...
Published in Osteoarthritis and Cartilage
Letter in response to “A prospective randomized comparison of neoprene vs thermoplast hand-based thumb spica splinting f...
Published in Osteoarthritis and Cartilage
FK506 protects against articular cartilage collagenous extra-cellular matrix degradation
Published in Osteoarthritis and Cartilage
ObjectiveOsteoarthritis (OA) is a non-rheumatologic joint disease characterized by progressive degeneration of the cartilage extra-cellular matrix (ECM), enhanced subchondral bone remodeling, activation of synovial macrophages and osteophyte growth. Inhibition of calcineurin (Cn) activity through tacrolimus (FK506) in in vitro monolayer chondrocyte...
Reducing dietary loading decreases mouse temporomandibular joint degradation induced by anterior crossbite prosthesis
...Published in Osteoarthritis and Cartilage
ObjectiveDietary loading has been reported to have an effect on temporomandibular joint (TMJ) remodeling via periodontal-muscular reflex. We therefore examined whether reducing dietary loading decreased TMJ degradation induced by the unilateral anterior crossbite prosthesis as we recently reported. MethodsForty 6-week-old female C57BL/6J mice were ...
2014 World Congress on Osteoarthritis
Published in Osteoarthritis and Cartilage
Bone sialoprotein as a potential key factor implicated in the pathophysiology of osteoarthritis
Published in Osteoarthritis and Cartilage
ObjectiveWe previously identified an association between bone sialoprotein (BSP) and osteoarthritic (OA) chondrocyte hypertrophy but the precise role of BSP in ostearthritis (OA) has not been extensively studied. This study aimed to confirm the association between BSP and OA chondrocyte hypertrophy, to define its effect on molecules produced by cho...
Biochemical evidence for gap junctions and Cx43 expression in immortalized human chondrocyte cell line: a potential mode...
Published in Osteoarthritis and Cartilage
ObjectiveThe development of chondrocytic cell lines has enabled the investigation of the role of cellular phenotype and mechanisms in articular cartilage biology and physiopathology of several rheumatic diseases. Among them, the T/C-28a2 cell line has become a common tool in cartilage research. Recent results from our group have revealed that prima...
Comment on Laufer et al. entitled “Effectiveness of thermal and athermal short-wave diathermy for the management of knee...
Published in Osteoarthritis and Cartilage
OARSI guidelines for the non-surgical management of knee osteoarthritis
...Published in Osteoarthritis and Cartilage
ObjectiveTo develop concise, up-to-date, patient-focused, evidence-based, expert consensus guidelines for the management of knee osteoarthritis (OA), intended to inform patients, physicians, and allied healthcare professionals worldwide. MethodThirteen experts from relevant medical disciplines (primary care, rheumatology, orthopedics, physical ther...
