Liu, Tao Zheng, Fenshuang Liu, Lin Zhou, Hua Shen, Tao Li, Yanping Zhang, Wei
Published in
Open Medicine
Background Paraquat (PQ) is a frequently used herbicide with neurotoxic effects after acute or chronic exposure. Although in vitro evidence supports the PQ toxicity to dopamine cells, its in vivo effects (especially the chronic exposure) remain ambiguous. In this study, we investigated the effect of chronic PQ exposure on the blood–brain barrier (B...
Liu, Min Ma, Jianning Bao, Kena Gu, Ye Zhao, Jing Ren, Dongmei Zhu, Fang Xu, Xiangdong
Published in
Open Medicine
Background The pathogenesis of cognitive impairment (CI) in coronary artery disease (CAD) patients is still unclear and numerous influence factors could affect the CI status. The current studies suggest that sleep quality and behavior pattern are significant influence factors associated with CAD susceptibility. Methods A total of 223 participants i...
Xu, Yi Fei, Xiangyong
Published in
Open Medicine
Objective To explore the relationship between cytokines such as interferon γ (IFN-γ), interleukin-10 (IL-10), and interleukin-6 (IL-6), as well as the severity of the condition, and serum zinc (Zn) and Fe levels in children with Mycoplasma pneumoniae infection. Methods A simple random sampling method was used to select 108 children with Mycoplasma ...
Opancina, Valentina Sebek, Vladimir Janjic, Vladimir
Published in
Open Medicine
Hidden information is the key to many security issues. If there is a reliable method to determine whether someone withholds information, many issues of this type can be resolved. However, until now, no method has proven to be reliable, but technical discoveries in the field of neuroimaging have caused a surge of new research in this area. Many neur...
Zhang, Juping Kong, Qian Zhang, Jibo Guo, Jun
Published in
Open Medicine
Background Gastric cancer (GC) is a leading cause of cancer-related morbidity and mortality globally. This meta-analysis was conducted to assess the impact of nutritional interventions on clinical outcomes in GC patients. Methods Comprehensive search was conducted across four medical databases to identify randomized controlled trials (RCTs) that ex...
Braun, Andreas Albert Atiya, Monika Göhner, Katja Hortobagyi, Tibor Burkhardt, Tobias Schreiner, Bettina
Published in
Open Medicine
Introduction Statin use can lead to various muscle-related issues, including benign creatine kinase (CK) elevations, myalgias, toxic myopathies, rhabdomyolysis, and immune-mediated necrotizing myositis (IMNM), which primarily affects older males. IMNM presents with proximal muscle weakness, elevated CK levels, and specific antibodies. Case presenta...
Hu, Xianwen Hu, Hongyu Li, Dandan Wang, Pan Cai, Jiong
Published in
Open Medicine
Purpose This study aimed to assess the biodistribution and bioactivity of the affibody molecular probe 99mTc-(HE)3ZHER2:V2, prepared by genetic recombination, and to investigate its potential for targeted human epidermal growth factor receptor 2 (HER2) imaging in SKOV3 ovarian cancer and MDA-MB-361 breast cancer xenografts. Methods Affibody molecul...
Lam, Ieng-Hou Chan, Chon-In Han, Meixia Li, Lixuan Yu, Hon-Ho
Published in
Open Medicine
Background The pathogenesis of inflammatory bowel disease (IBD) is closely associated with the dysfunction of the intestinal epithelial barrier, leading to increased bacterial translocation, leukocyte infiltration, and mucosal injury, which may act as a pivotal or incipient event in the pathophysiology of the disorder. The primary objective of this...
Cao, Lulu Ren, Yunhong Wen, Fang Du, Juan He, Mei Huang, Huaping
Published in
Open Medicine
Background Emergence agitation (EA) is a behavioural disturbance encountered during the recovery phase of patients following general anaesthesia. It is characterised by restlessness, involuntary limb movements, and drainage tube withdrawal and may significantly harm patients and medical staff. The mechanism of EA has not been fully understood and i...
Abdulqader, Goran Mohammed Raouf
Published in
Open Medicine
Background Most gastrointestinal polyps are asymptomatic; therefore, assessing symptoms associated with cancer and precancerous polyps is essential. Objectives The aim of this study was to study the histopathology, number, distribution, and degree of polyps’ dysplasia in terms of age, gender, and clinical presentation. Methods This study was perfor...
